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Anti-SC5AA/ SLC5A10/ SGLT-5 monoclonal antibody
Anti-SC5AA/ SLC5A10/ SGLT-5 antibody for FACS & in-vivo assay
Go to SLC5A10/SLC5A10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1648-Ab-1/ GM-Tg-hg-MP1648-Ab-2 | Anti-Human SLC5A10 monoclonal antibody | Human |
| GM-Tg-rg-MP1648-Ab-1/ GM-Tg-rg-MP1648-Ab-2 | Anti-Rat SLC5A10 monoclonal antibody | Rat |
| GM-Tg-mg-MP1648-Ab-1/ GM-Tg-mg-MP1648-Ab-2 | Anti-Mouse SLC5A10 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1648-Ab-1/ GM-Tg-cynog-MP1648-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC5A10 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1648-Ab-1/ GM-Tg-felg-MP1648-Ab-2 | Anti-Feline SLC5A10 monoclonal antibody | Feline |
| GM-Tg-cang-MP1648-Ab-1/ GM-Tg-cang-MP1648-Ab-2 | Anti-Canine SLC5A10 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1648-Ab-1/ GM-Tg-bovg-MP1648-Ab-2 | Anti-Bovine SLC5A10 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1648-Ab-1/ GM-Tg-equg-MP1648-Ab-2 | Anti-Equine SLC5A10 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1648-Ab-1/ GM-Tg-hg-MP1648-Ab-2; GM-Tg-rg-MP1648-Ab-1/ GM-Tg-rg-MP1648-Ab-2; GM-Tg-mg-MP1648-Ab-1/ GM-Tg-mg-MP1648-Ab-2; GM-Tg-cynog-MP1648-Ab-1/ GM-Tg-cynog-MP1648-Ab-2; GM-Tg-felg-MP1648-Ab-1/ GM-Tg-felg-MP1648-Ab-2; GM-Tg-cang-MP1648-Ab-1/ GM-Tg-cang-MP1648-Ab-2; GM-Tg-bovg-MP1648-Ab-1/ GM-Tg-bovg-MP1648-Ab-2; GM-Tg-equg-MP1648-Ab-1/ GM-Tg-equg-MP1648-Ab-2 |
| Products Name | Anti-SLC5A10 monoclonal antibody |
| Format | mab |
| Target Name | SLC5A10 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC5A10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SC5AA/ SLC5A10/ SGLT-5 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1648 |
| Target Name | SLC5A10 |
| Gene ID | 125206,109342,303205,709069,102156040,101098413,407227,100051238 |
| Gene Symbol and Synonyms | C330021F16Rik,SGLT-5,SGLT5,SLC5A10 |
| Uniprot Accession | A0PJK1,Q6R4Q5 |
| Uniprot Entry Name | SC5AA_HUMAN,SC5AA_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000154025 |
| Target Classification | N/A |
The target: SLC5A10, gene name: SLC5A10, also named as SGLT-5, SGLT5. This gene is a member of the sodium/glucose transporter family. Members of this family are sodium-dependent transporters and can be divided into two subfamilies based on sequence homology, one that co-transports sugars and the second that transports molecules such as ascorbate, choline, iodide, lipoate, monocaroboxylates, and pantothenate. The protein encoded by this gene has the highest affinity for mannose and has been reported to be most highly expressed in the kidney. This protein may function as a kidney-specific, sodium-dependent mannose and fructose co-transporter. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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