Anti-SC5AB/ SLC5A11/ KST1 monoclonal antibody

Anti-SC5AB/ SLC5A11/ KST1 antibody for FACS & in-vivo assay

Target products collectionGo to SLC5A11/SLC5A11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1649-Ab-1/ GM-Tg-hg-MP1649-Ab-2Anti-Human SLC5A11 monoclonal antibodyHuman
GM-Tg-rg-MP1649-Ab-1/ GM-Tg-rg-MP1649-Ab-2Anti-Rat SLC5A11 monoclonal antibodyRat
GM-Tg-mg-MP1649-Ab-1/ GM-Tg-mg-MP1649-Ab-2Anti-Mouse SLC5A11 monoclonal antibodyMouse
GM-Tg-cynog-MP1649-Ab-1/ GM-Tg-cynog-MP1649-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC5A11 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1649-Ab-1/ GM-Tg-felg-MP1649-Ab-2Anti-Feline SLC5A11 monoclonal antibodyFeline
GM-Tg-cang-MP1649-Ab-1/ GM-Tg-cang-MP1649-Ab-2Anti-Canine SLC5A11 monoclonal antibodyCanine
GM-Tg-bovg-MP1649-Ab-1/ GM-Tg-bovg-MP1649-Ab-2Anti-Bovine SLC5A11 monoclonal antibodyBovine
GM-Tg-equg-MP1649-Ab-1/ GM-Tg-equg-MP1649-Ab-2Anti-Equine SLC5A11 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1649-Ab-1/ GM-Tg-hg-MP1649-Ab-2; GM-Tg-rg-MP1649-Ab-1/ GM-Tg-rg-MP1649-Ab-2;
GM-Tg-mg-MP1649-Ab-1/ GM-Tg-mg-MP1649-Ab-2; GM-Tg-cynog-MP1649-Ab-1/ GM-Tg-cynog-MP1649-Ab-2;
GM-Tg-felg-MP1649-Ab-1/ GM-Tg-felg-MP1649-Ab-2; GM-Tg-cang-MP1649-Ab-1/ GM-Tg-cang-MP1649-Ab-2;
GM-Tg-bovg-MP1649-Ab-1/ GM-Tg-bovg-MP1649-Ab-2; GM-Tg-equg-MP1649-Ab-1/ GM-Tg-equg-MP1649-Ab-2
Products NameAnti-SLC5A11 monoclonal antibody
Formatmab
Target NameSLC5A11
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC5A11 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SC5AB/ SLC5A11/ KST1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1649
    Target NameSLC5A11
    Gene ID115584,233836,252854,701816,489965,101097034,539084,100068437
    Gene Symbol and Synonyms2010013B02Rik,KST1,RKST1,RKST2,SGLT6,Slc5a10,SLC5A11,SMIT2
    Uniprot AccessionQ8WWX8,Q9Z1F2,Q3ZC26
    Uniprot Entry NameSC5AB_HUMAN,SC5AB_RAT,SC5AB_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000158865
    Target ClassificationN/A

    The target: SLC5A11, gene name: SLC5A11, also named as KST1, RKST1, SGLT6, SMIT2. Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.