Anti-S6A18/ SLC6A18/ Xtrp2 monoclonal antibody

Anti-S6A18/ SLC6A18/ Xtrp2 antibody for FACS & in-vivo assay

Target products collectionGo to SLC6A18/SLC6A18 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1656-Ab-1/ GM-Tg-hg-MP1656-Ab-2Anti-Human SLC6A18 monoclonal antibodyHuman
GM-Tg-rg-MP1656-Ab-1/ GM-Tg-rg-MP1656-Ab-2Anti-Rat SLC6A18 monoclonal antibodyRat
GM-Tg-mg-MP1656-Ab-1/ GM-Tg-mg-MP1656-Ab-2Anti-Mouse SLC6A18 monoclonal antibodyMouse
GM-Tg-cynog-MP1656-Ab-1/ GM-Tg-cynog-MP1656-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC6A18 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1656-Ab-1/ GM-Tg-felg-MP1656-Ab-2Anti-Feline SLC6A18 monoclonal antibodyFeline
GM-Tg-cang-MP1656-Ab-1/ GM-Tg-cang-MP1656-Ab-2Anti-Canine SLC6A18 monoclonal antibodyCanine
GM-Tg-bovg-MP1656-Ab-1/ GM-Tg-bovg-MP1656-Ab-2Anti-Bovine SLC6A18 monoclonal antibodyBovine
GM-Tg-equg-MP1656-Ab-1/ GM-Tg-equg-MP1656-Ab-2Anti-Equine SLC6A18 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1656-Ab-1/ GM-Tg-hg-MP1656-Ab-2; GM-Tg-rg-MP1656-Ab-1/ GM-Tg-rg-MP1656-Ab-2;
GM-Tg-mg-MP1656-Ab-1/ GM-Tg-mg-MP1656-Ab-2; GM-Tg-cynog-MP1656-Ab-1/ GM-Tg-cynog-MP1656-Ab-2;
GM-Tg-felg-MP1656-Ab-1/ GM-Tg-felg-MP1656-Ab-2; GM-Tg-cang-MP1656-Ab-1/ GM-Tg-cang-MP1656-Ab-2;
GM-Tg-bovg-MP1656-Ab-1/ GM-Tg-bovg-MP1656-Ab-2; GM-Tg-equg-MP1656-Ab-1/ GM-Tg-equg-MP1656-Ab-2
Products NameAnti-SLC6A18 monoclonal antibody
Formatmab
Target NameSLC6A18
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC6A18 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S6A18/ SLC6A18/ Xtrp2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1656
    Target NameSLC6A18
    Gene ID348932,22598,29323,723065,478631,101081196,527659,100146923
    Gene Symbol and SynonymsB0AT3,D630001K16Rik,Rosit,SLC6A18,Xt2,Xtrp2
    Uniprot AccessionQ96N87,Q62687
    Uniprot Entry NameS6A18_HUMAN,S6A18_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164363
    Target ClassificationN/A

    The target: SLC6A18, gene name: SLC6A18, also named as Xtrp2. The SLC6 family of proteins, which includes SLC6A18, act as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Apr 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.