Anti-LAT2/ SLC7A8/ LPI-PC1 monoclonal antibody

Anti-LAT2/ SLC7A8/ LPI-PC1 antibody for FACS & in-vivo assay

Target products collectionGo to SLC7A8/SLC7A8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1667-Ab-1/ GM-Tg-hg-MP1667-Ab-2Anti-Human SLC7A8 monoclonal antibodyHuman
GM-Tg-rg-MP1667-Ab-1/ GM-Tg-rg-MP1667-Ab-2Anti-Rat SLC7A8 monoclonal antibodyRat
GM-Tg-mg-MP1667-Ab-1/ GM-Tg-mg-MP1667-Ab-2Anti-Mouse SLC7A8 monoclonal antibodyMouse
GM-Tg-cynog-MP1667-Ab-1/ GM-Tg-cynog-MP1667-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC7A8 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1667-Ab-1/ GM-Tg-felg-MP1667-Ab-2Anti-Feline SLC7A8 monoclonal antibodyFeline
GM-Tg-cang-MP1667-Ab-1/ GM-Tg-cang-MP1667-Ab-2Anti-Canine SLC7A8 monoclonal antibodyCanine
GM-Tg-bovg-MP1667-Ab-1/ GM-Tg-bovg-MP1667-Ab-2Anti-Bovine SLC7A8 monoclonal antibodyBovine
GM-Tg-equg-MP1667-Ab-1/ GM-Tg-equg-MP1667-Ab-2Anti-Equine SLC7A8 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1667-Ab-1/ GM-Tg-hg-MP1667-Ab-2; GM-Tg-rg-MP1667-Ab-1/ GM-Tg-rg-MP1667-Ab-2;
GM-Tg-mg-MP1667-Ab-1/ GM-Tg-mg-MP1667-Ab-2; GM-Tg-cynog-MP1667-Ab-1/ GM-Tg-cynog-MP1667-Ab-2;
GM-Tg-felg-MP1667-Ab-1/ GM-Tg-felg-MP1667-Ab-2; GM-Tg-cang-MP1667-Ab-1/ GM-Tg-cang-MP1667-Ab-2;
GM-Tg-bovg-MP1667-Ab-1/ GM-Tg-bovg-MP1667-Ab-2; GM-Tg-equg-MP1667-Ab-1/ GM-Tg-equg-MP1667-Ab-2
Products NameAnti-SLC7A8 monoclonal antibody
Formatmab
Target NameSLC7A8
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC7A8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species LAT2/ SLC7A8/ LPI-PC1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm005003mouse Slc7a8 Lentivirus plasmid
    ORF Viral VectorvGMLPm005003mouse Slc7a8 Lentivirus particle


    Target information

    Target IDGM-MP1667
    Target NameSLC7A8
    Gene ID23428,50934,84551,713511,490608,101094106,536818,100052453
    Gene Symbol and SynonymsLAT2,Lat4,LPI-PC1,SLC7A8
    Uniprot AccessionQ9UHI5,Q9WVR6
    Uniprot Entry NameLAT2_HUMAN,LAT2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000092068
    Target ClassificationN/A

    The target: SLC7A8, gene name: SLC7A8, also named as LAT2, LPI-PC1. Enables several functions, including neutral amino acid transmembrane transporter activity; thyroid hormone transmembrane transporter activity; and toxin transmembrane transporter activity. Involved in L-alanine import across plasma membrane; L-leucine import across plasma membrane; and thyroid hormone transport. Located in plasma membrane. Part of basolateral plasma membrane and microvillus membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.