Anti-SL9A2/ SLC9A2/ NHE2 monoclonal antibody

Anti-SL9A2/ SLC9A2/ NHE2 antibody for FACS & in-vivo assay

Target products collectionGo to SLC9A2/SLC9A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1671-Ab-1/ GM-Tg-hg-MP1671-Ab-2Anti-Human SLC9A2 monoclonal antibodyHuman
GM-Tg-rg-MP1671-Ab-1/ GM-Tg-rg-MP1671-Ab-2Anti-Rat SLC9A2 monoclonal antibodyRat
GM-Tg-mg-MP1671-Ab-1/ GM-Tg-mg-MP1671-Ab-2Anti-Mouse SLC9A2 monoclonal antibodyMouse
GM-Tg-cynog-MP1671-Ab-1/ GM-Tg-cynog-MP1671-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC9A2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1671-Ab-1/ GM-Tg-felg-MP1671-Ab-2Anti-Feline SLC9A2 monoclonal antibodyFeline
GM-Tg-cang-MP1671-Ab-1/ GM-Tg-cang-MP1671-Ab-2Anti-Canine SLC9A2 monoclonal antibodyCanine
GM-Tg-bovg-MP1671-Ab-1/ GM-Tg-bovg-MP1671-Ab-2Anti-Bovine SLC9A2 monoclonal antibodyBovine
GM-Tg-equg-MP1671-Ab-1/ GM-Tg-equg-MP1671-Ab-2Anti-Equine SLC9A2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1671-Ab-1/ GM-Tg-hg-MP1671-Ab-2; GM-Tg-rg-MP1671-Ab-1/ GM-Tg-rg-MP1671-Ab-2;
GM-Tg-mg-MP1671-Ab-1/ GM-Tg-mg-MP1671-Ab-2; GM-Tg-cynog-MP1671-Ab-1/ GM-Tg-cynog-MP1671-Ab-2;
GM-Tg-felg-MP1671-Ab-1/ GM-Tg-felg-MP1671-Ab-2; GM-Tg-cang-MP1671-Ab-1/ GM-Tg-cang-MP1671-Ab-2;
GM-Tg-bovg-MP1671-Ab-1/ GM-Tg-bovg-MP1671-Ab-2; GM-Tg-equg-MP1671-Ab-1/ GM-Tg-equg-MP1671-Ab-2
Products NameAnti-SLC9A2 monoclonal antibody
Formatmab
Target NameSLC9A2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC9A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SL9A2/ SLC9A2/ NHE2 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP001737human SLC9A2 Lentivirus particle
    ORF Viral VectorpGMLP001737human SLC9A2 Lentivirus plasmid


    Target information

    Target IDGM-MP1671
    Target NameSLC9A2
    Gene ID6549,226999,24783,712199,474546,101084614,526134,100034108
    Gene Symbol and Synonyms2210416H12Rik,4932415O19Rik,NHE-2,NHE2,SLC9A2
    Uniprot AccessionQ9UBY0,P48763
    Uniprot Entry NameSL9A2_HUMAN,SL9A2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000115616
    Target ClassificationN/A

    The target: SLC9A2, gene name: SLC9A2, also named as NHE2. This gene encodes a member of the sodium-hydrogen exchanger (NHE) protein family. These proteins are involved in sodium-ion transport by exchanging intracellular hydrogen ions to external sodium ions and help in the regulation of cell pH and volume. The encoded protein is localized to the apical membrane and is involved in apical absorption of sodium. [provided by RefSeq, Jun 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.