Anti-SL9A6/ SLC9A6/ MRSA monoclonal antibody

Anti-SL9A6/ SLC9A6/ MRSA antibody for FACS & in-vivo assay

Target products collectionGo to SLC9A6/SLC9A6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1674-Ab-1/ GM-Tg-hg-MP1674-Ab-2Anti-Human SLC9A6 monoclonal antibodyHuman
GM-Tg-rg-MP1674-Ab-1/ GM-Tg-rg-MP1674-Ab-2Anti-Rat SLC9A6 monoclonal antibodyRat
GM-Tg-mg-MP1674-Ab-1/ GM-Tg-mg-MP1674-Ab-2Anti-Mouse SLC9A6 monoclonal antibodyMouse
GM-Tg-cynog-MP1674-Ab-1/ GM-Tg-cynog-MP1674-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC9A6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1674-Ab-1/ GM-Tg-felg-MP1674-Ab-2Anti-Feline SLC9A6 monoclonal antibodyFeline
GM-Tg-cang-MP1674-Ab-1/ GM-Tg-cang-MP1674-Ab-2Anti-Canine SLC9A6 monoclonal antibodyCanine
GM-Tg-bovg-MP1674-Ab-1/ GM-Tg-bovg-MP1674-Ab-2Anti-Bovine SLC9A6 monoclonal antibodyBovine
GM-Tg-equg-MP1674-Ab-1/ GM-Tg-equg-MP1674-Ab-2Anti-Equine SLC9A6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1674-Ab-1/ GM-Tg-hg-MP1674-Ab-2; GM-Tg-rg-MP1674-Ab-1/ GM-Tg-rg-MP1674-Ab-2;
GM-Tg-mg-MP1674-Ab-1/ GM-Tg-mg-MP1674-Ab-2; GM-Tg-cynog-MP1674-Ab-1/ GM-Tg-cynog-MP1674-Ab-2;
GM-Tg-felg-MP1674-Ab-1/ GM-Tg-felg-MP1674-Ab-2; GM-Tg-cang-MP1674-Ab-1/ GM-Tg-cang-MP1674-Ab-2;
GM-Tg-bovg-MP1674-Ab-1/ GM-Tg-bovg-MP1674-Ab-2; GM-Tg-equg-MP1674-Ab-1/ GM-Tg-equg-MP1674-Ab-2
Products NameAnti-SLC9A6 monoclonal antibody
Formatmab
Target NameSLC9A6
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC9A6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SL9A6/ SLC9A6/ MRSA VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm003646mouse Slc9a6 Lentivirus plasmid
    ORF Viral VectorvGMLPm003646mouse Slc9a6 Lentivirus particle


    Target information

    Target IDGM-MP1674
    Target NameSLC9A6
    Gene ID10479,236794,302863,710429,481060,101097796,533137,100057106
    Gene Symbol and Synonyms3732426M05,6430520C02Rik,mKIAA0267,MRSA,MRXSCH,NHE-6,NHE6,RGD1563582,SLC9A6
    Uniprot AccessionQ92581,D3ZJ86
    Uniprot Entry NameSL9A6_HUMAN,D3ZJ86_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000198689
    Target ClassificationN/A

    The target: SLC9A6, gene name: SLC9A6, also named as MRSA, NHE6. This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic cognitive disability, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.