Anti-SL9A7/ SLC9A7/ NHE-7 monoclonal antibody

Anti-SL9A7/ SLC9A7/ NHE-7 antibody for FACS & in-vivo assay

Target products collectionGo to SLC9A7/SLC9A7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1675-Ab-1/ GM-Tg-hg-MP1675-Ab-2Anti-Human SLC9A7 monoclonal antibodyHuman
GM-Tg-rg-MP1675-Ab-1/ GM-Tg-rg-MP1675-Ab-2Anti-Rat SLC9A7 monoclonal antibodyRat
GM-Tg-mg-MP1675-Ab-1/ GM-Tg-mg-MP1675-Ab-2Anti-Mouse SLC9A7 monoclonal antibodyMouse
GM-Tg-cynog-MP1675-Ab-1/ GM-Tg-cynog-MP1675-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC9A7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1675-Ab-1/ GM-Tg-felg-MP1675-Ab-2Anti-Feline SLC9A7 monoclonal antibodyFeline
GM-Tg-cang-MP1675-Ab-1/ GM-Tg-cang-MP1675-Ab-2Anti-Canine SLC9A7 monoclonal antibodyCanine
GM-Tg-bovg-MP1675-Ab-1/ GM-Tg-bovg-MP1675-Ab-2Anti-Bovine SLC9A7 monoclonal antibodyBovine
GM-Tg-equg-MP1675-Ab-1/ GM-Tg-equg-MP1675-Ab-2Anti-Equine SLC9A7 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1675-Ab-1/ GM-Tg-hg-MP1675-Ab-2; GM-Tg-rg-MP1675-Ab-1/ GM-Tg-rg-MP1675-Ab-2;
GM-Tg-mg-MP1675-Ab-1/ GM-Tg-mg-MP1675-Ab-2; GM-Tg-cynog-MP1675-Ab-1/ GM-Tg-cynog-MP1675-Ab-2;
GM-Tg-felg-MP1675-Ab-1/ GM-Tg-felg-MP1675-Ab-2; GM-Tg-cang-MP1675-Ab-1/ GM-Tg-cang-MP1675-Ab-2;
GM-Tg-bovg-MP1675-Ab-1/ GM-Tg-bovg-MP1675-Ab-2; GM-Tg-equg-MP1675-Ab-1/ GM-Tg-equg-MP1675-Ab-2
Products NameAnti-SLC9A7 monoclonal antibody
Formatmab
Target NameSLC9A7
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC9A7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SL9A7/ SLC9A7/ NHE-7 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1675
    Target NameSLC9A7
    Gene ID84679,236727,317170,710906,609144,101098119,522505,100060383
    Gene Symbol and Synonyms6330509M05Rik,A530087D17Rik,MRX108,NHE-7,NHE7,SLC9A6,SLC9A7
    Uniprot AccessionQ96T83
    Uniprot Entry NameSL9A7_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000065923
    Target ClassificationN/A

    The target: SLC9A7, gene name: SLC9A7, also named as NHE-7, NHE7, SLC9A6. This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.