Anti-SL9C1/ SLC9C1/ NHE monoclonal antibody

Anti-SL9C1/ SLC9C1/ NHE antibody for FACS & in-vivo assay

Target products collectionGo to SLC9C1/SLC9C1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1679-Ab-1/ GM-Tg-hg-MP1679-Ab-2Anti-Human SLC9C1 monoclonal antibodyHuman
GM-Tg-rg-MP1679-Ab-1/ GM-Tg-rg-MP1679-Ab-2Anti-Rat SLC9C1 monoclonal antibodyRat
GM-Tg-mg-MP1679-Ab-1/ GM-Tg-mg-MP1679-Ab-2Anti-Mouse SLC9C1 monoclonal antibodyMouse
GM-Tg-cynog-MP1679-Ab-1/ GM-Tg-cynog-MP1679-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC9C1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1679-Ab-1/ GM-Tg-felg-MP1679-Ab-2Anti-Feline SLC9C1 monoclonal antibodyFeline
GM-Tg-cang-MP1679-Ab-1/ GM-Tg-cang-MP1679-Ab-2Anti-Canine SLC9C1 monoclonal antibodyCanine
GM-Tg-bovg-MP1679-Ab-1/ GM-Tg-bovg-MP1679-Ab-2Anti-Bovine SLC9C1 monoclonal antibodyBovine
GM-Tg-equg-MP1679-Ab-1/ GM-Tg-equg-MP1679-Ab-2Anti-Equine SLC9C1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1679-Ab-1/ GM-Tg-hg-MP1679-Ab-2; GM-Tg-rg-MP1679-Ab-1/ GM-Tg-rg-MP1679-Ab-2;
GM-Tg-mg-MP1679-Ab-1/ GM-Tg-mg-MP1679-Ab-2; GM-Tg-cynog-MP1679-Ab-1/ GM-Tg-cynog-MP1679-Ab-2;
GM-Tg-felg-MP1679-Ab-1/ GM-Tg-felg-MP1679-Ab-2; GM-Tg-cang-MP1679-Ab-1/ GM-Tg-cang-MP1679-Ab-2;
GM-Tg-bovg-MP1679-Ab-1/ GM-Tg-bovg-MP1679-Ab-2; GM-Tg-equg-MP1679-Ab-1/ GM-Tg-equg-MP1679-Ab-2
Products NameAnti-SLC9C1 monoclonal antibody
Formatmab
Target NameSLC9C1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC9C1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SL9C1/ SLC9C1/ NHE VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1679
    Target NameSLC9C1
    Gene ID285335,208169,288117,708000,478563,101095603,104968609,100071525
    Gene Symbol and SynonymsGm610,NHE,NHE-10,SLC9A10,SLC9C1,sNHE,sperm-NHE,spermNHE
    Uniprot AccessionQ4G0N8
    Uniprot Entry NameSL9C1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000172139
    Target ClassificationN/A

    The target: SLC9C1, gene name: SLC9C1, also named as NHE, NHE-10, SLC9A10, sperm-NHE. SLC9A10 is a member of the sodium-hydrogen exchanger (NHE) family (see SLC9A1, MIM 107310) and is required for male fertility and sperm motility (Wang et al., 2003 [PubMed 14634667]).[supplied by OMIM, Apr 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.