Anti-SLIK3/ SLITRK3 monoclonal antibody

Anti-SLIK3/ SLITRK3 antibody for FACS & in-vivo assay

Target products collectionGo to SLITRK3/SLITRK3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1685-Ab-1/ GM-Tg-hg-MP1685-Ab-2Anti-Human SLITRK3 monoclonal antibodyHuman
GM-Tg-rg-MP1685-Ab-1/ GM-Tg-rg-MP1685-Ab-2Anti-Rat SLITRK3 monoclonal antibodyRat
GM-Tg-mg-MP1685-Ab-1/ GM-Tg-mg-MP1685-Ab-2Anti-Mouse SLITRK3 monoclonal antibodyMouse
GM-Tg-cynog-MP1685-Ab-1/ GM-Tg-cynog-MP1685-Ab-2Anti-Cynomolgus/ Rhesus macaque SLITRK3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1685-Ab-1/ GM-Tg-felg-MP1685-Ab-2Anti-Feline SLITRK3 monoclonal antibodyFeline
GM-Tg-cang-MP1685-Ab-1/ GM-Tg-cang-MP1685-Ab-2Anti-Canine SLITRK3 monoclonal antibodyCanine
GM-Tg-bovg-MP1685-Ab-1/ GM-Tg-bovg-MP1685-Ab-2Anti-Bovine SLITRK3 monoclonal antibodyBovine
GM-Tg-equg-MP1685-Ab-1/ GM-Tg-equg-MP1685-Ab-2Anti-Equine SLITRK3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1685-Ab-1/ GM-Tg-hg-MP1685-Ab-2; GM-Tg-rg-MP1685-Ab-1/ GM-Tg-rg-MP1685-Ab-2;
GM-Tg-mg-MP1685-Ab-1/ GM-Tg-mg-MP1685-Ab-2; GM-Tg-cynog-MP1685-Ab-1/ GM-Tg-cynog-MP1685-Ab-2;
GM-Tg-felg-MP1685-Ab-1/ GM-Tg-felg-MP1685-Ab-2; GM-Tg-cang-MP1685-Ab-1/ GM-Tg-cang-MP1685-Ab-2;
GM-Tg-bovg-MP1685-Ab-1/ GM-Tg-bovg-MP1685-Ab-2; GM-Tg-equg-MP1685-Ab-1/ GM-Tg-equg-MP1685-Ab-2
Products NameAnti-SLITRK3 monoclonal antibody
Formatmab
Target NameSLITRK3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLITRK3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SLIK3/ SLITRK3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1685
    Target NameSLITRK3
    Gene ID22865,386750,310519,700660,608925,101091137,527364,100063273
    Gene Symbol and SynonymsSLITRK3,ST3
    Uniprot AccessionO94933
    Uniprot Entry NameSLIK3_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000121871
    Target ClassificationN/A

    The target: SLITRK3, gene name: SLITRK3, also named as . This gene encodes a member of the Slitrk family of structurally related transmembrane proteins that are involved in controlling neurite outgrowth. The encoded protein contains two leucine-rich repeat (LRR) domains and a C-terminal domain that is partially similar to Trk neurotrophin receptor protein. Enhanced expression of this gene was found in tissue from several different types of tumors. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Jan 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.