Anti-SMIM1/ Vel monoclonal antibody

Anti-SMIM1/ Vel antibody for FACS & in-vivo assay

Target products collectionGo to SMIM1/SMIM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1689-Ab-1/ GM-Tg-hg-MP1689-Ab-2Anti-Human SMIM1 monoclonal antibodyHuman
GM-Tg-rg-MP1689-Ab-1/ GM-Tg-rg-MP1689-Ab-2Anti-Rat SMIM1 monoclonal antibodyRat
GM-Tg-mg-MP1689-Ab-1/ GM-Tg-mg-MP1689-Ab-2Anti-Mouse SMIM1 monoclonal antibodyMouse
GM-Tg-cynog-MP1689-Ab-1/ GM-Tg-cynog-MP1689-Ab-2Anti-Cynomolgus/ Rhesus macaque SMIM1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1689-Ab-1/ GM-Tg-felg-MP1689-Ab-2Anti-Feline SMIM1 monoclonal antibodyFeline
GM-Tg-cang-MP1689-Ab-1/ GM-Tg-cang-MP1689-Ab-2Anti-Canine SMIM1 monoclonal antibodyCanine
GM-Tg-bovg-MP1689-Ab-1/ GM-Tg-bovg-MP1689-Ab-2Anti-Bovine SMIM1 monoclonal antibodyBovine
GM-Tg-equg-MP1689-Ab-1/ GM-Tg-equg-MP1689-Ab-2Anti-Equine SMIM1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1689-Ab-1/ GM-Tg-hg-MP1689-Ab-2; GM-Tg-rg-MP1689-Ab-1/ GM-Tg-rg-MP1689-Ab-2;
GM-Tg-mg-MP1689-Ab-1/ GM-Tg-mg-MP1689-Ab-2; GM-Tg-cynog-MP1689-Ab-1/ GM-Tg-cynog-MP1689-Ab-2;
GM-Tg-felg-MP1689-Ab-1/ GM-Tg-felg-MP1689-Ab-2; GM-Tg-cang-MP1689-Ab-1/ GM-Tg-cang-MP1689-Ab-2;
GM-Tg-bovg-MP1689-Ab-1/ GM-Tg-bovg-MP1689-Ab-2; GM-Tg-equg-MP1689-Ab-1/ GM-Tg-equg-MP1689-Ab-2
Products NameAnti-SMIM1 monoclonal antibody
Formatmab
Target NameSMIM1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SMIM1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SMIM1/ Vel VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1689
    Target NameSMIM1
    Gene ID388588,68859,500595,695502,100856531,101091883,100302586,100630652
    Gene Symbol and Synonyms0610011H04Rik,1190007F08Rik,2700009I11Rik,RGD1564257,SMIM1,Vel
    Uniprot AccessionB2RUZ4
    Uniprot Entry NameSMIM1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000235169
    Target ClassificationN/A

    The target: SMIM1, gene name: SMIM1, also named as Vel. This gene encodes a small, conserved protein that participates in red blood cell formation. The encoded protein is localized to the cell membrane and is the antigen for the Vel blood group. Alternative splicing results in different transcript variants that encode the same protein. [provided by RefSeq, Dec 2013].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.