Anti-SPRN/ SHADOO/ SHO monoclonal antibody

Anti-SPRN/ SHADOO/ SHO antibody for FACS & in-vivo assay

Target products collectionGo to SPRN/SPRN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1708-Ab-1/ GM-Tg-hg-MP1708-Ab-2Anti-Human SPRN monoclonal antibodyHuman
GM-Tg-rg-MP1708-Ab-1/ GM-Tg-rg-MP1708-Ab-2Anti-Rat SPRN monoclonal antibodyRat
GM-Tg-mg-MP1708-Ab-1/ GM-Tg-mg-MP1708-Ab-2Anti-Mouse SPRN monoclonal antibodyMouse
GM-Tg-cynog-MP1708-Ab-1/ GM-Tg-cynog-MP1708-Ab-2Anti-Cynomolgus/ Rhesus macaque SPRN monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1708-Ab-1/ GM-Tg-felg-MP1708-Ab-2Anti-Feline SPRN monoclonal antibodyFeline
GM-Tg-cang-MP1708-Ab-1/ GM-Tg-cang-MP1708-Ab-2Anti-Canine SPRN monoclonal antibodyCanine
GM-Tg-bovg-MP1708-Ab-1/ GM-Tg-bovg-MP1708-Ab-2Anti-Bovine SPRN monoclonal antibodyBovine
GM-Tg-equg-MP1708-Ab-1/ GM-Tg-equg-MP1708-Ab-2Anti-Equine SPRN monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1708-Ab-1/ GM-Tg-hg-MP1708-Ab-2; GM-Tg-rg-MP1708-Ab-1/ GM-Tg-rg-MP1708-Ab-2;
GM-Tg-mg-MP1708-Ab-1/ GM-Tg-mg-MP1708-Ab-2; GM-Tg-cynog-MP1708-Ab-1/ GM-Tg-cynog-MP1708-Ab-2;
GM-Tg-felg-MP1708-Ab-1/ GM-Tg-felg-MP1708-Ab-2; GM-Tg-cang-MP1708-Ab-1/ GM-Tg-cang-MP1708-Ab-2;
GM-Tg-bovg-MP1708-Ab-1/ GM-Tg-bovg-MP1708-Ab-2; GM-Tg-equg-MP1708-Ab-1/ GM-Tg-equg-MP1708-Ab-2
Products NameAnti-SPRN monoclonal antibody
Formatmab
Target NameSPRN
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SPRN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SPRN/ SHADOO/ SHO VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1708
    Target NameSPRN
    Gene ID503542,212518,541462,719900,100855950,102902356,616266,111772531
    Gene Symbol and SynonymsbA108K14.1,C630041J07,SHADOO,SHO,SPRN
    Uniprot AccessionQ5BIV9,Q5BIV7,A0RZB4
    Uniprot Entry NameSPRN_HUMAN,SPRN_RAT,SPRN_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000203772
    Target ClassificationN/A

    The target: SPRN, gene name: SPRN, also named as SHADOO, SHO, bA108K14.1. Predicted to enable nucleic acid binding activity. Predicted to be involved in protein import into nucleus. Predicted to be located in membrane. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.