Anti-SIA7F/ ST6GALNAC6/ SIAT7-F monoclonal antibody

Anti-SIA7F/ ST6GALNAC6/ SIAT7-F antibody for FACS & in-vivo assay

Target products collectionGo to ST6GALNAC6/ST6GALNAC6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1711-Ab-1/ GM-Tg-hg-MP1711-Ab-2Anti-Human ST6GALNAC6 monoclonal antibodyHuman
GM-Tg-rg-MP1711-Ab-1/ GM-Tg-rg-MP1711-Ab-2Anti-Rat ST6GALNAC6 monoclonal antibodyRat
GM-Tg-mg-MP1711-Ab-1/ GM-Tg-mg-MP1711-Ab-2Anti-Mouse ST6GALNAC6 monoclonal antibodyMouse
GM-Tg-cynog-MP1711-Ab-1/ GM-Tg-cynog-MP1711-Ab-2Anti-Cynomolgus/ Rhesus macaque ST6GALNAC6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1711-Ab-1/ GM-Tg-felg-MP1711-Ab-2Anti-Feline ST6GALNAC6 monoclonal antibodyFeline
GM-Tg-cang-MP1711-Ab-1/ GM-Tg-cang-MP1711-Ab-2Anti-Canine ST6GALNAC6 monoclonal antibodyCanine
GM-Tg-bovg-MP1711-Ab-1/ GM-Tg-bovg-MP1711-Ab-2Anti-Bovine ST6GALNAC6 monoclonal antibodyBovine
GM-Tg-equg-MP1711-Ab-1/ GM-Tg-equg-MP1711-Ab-2Anti-Equine ST6GALNAC6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1711-Ab-1/ GM-Tg-hg-MP1711-Ab-2; GM-Tg-rg-MP1711-Ab-1/ GM-Tg-rg-MP1711-Ab-2;
GM-Tg-mg-MP1711-Ab-1/ GM-Tg-mg-MP1711-Ab-2; GM-Tg-cynog-MP1711-Ab-1/ GM-Tg-cynog-MP1711-Ab-2;
GM-Tg-felg-MP1711-Ab-1/ GM-Tg-felg-MP1711-Ab-2; GM-Tg-cang-MP1711-Ab-1/ GM-Tg-cang-MP1711-Ab-2;
GM-Tg-bovg-MP1711-Ab-1/ GM-Tg-bovg-MP1711-Ab-2; GM-Tg-equg-MP1711-Ab-1/ GM-Tg-equg-MP1711-Ab-2
Products NameAnti-ST6GALNAC6 monoclonal antibody
Formatmab
Target NameST6GALNAC6
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ST6GALNAC6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SIA7F/ ST6GALNAC6/ SIAT7-F VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1711
    Target NameST6GALNAC6
    Gene ID30815,50935,407765,706120,491324,101094218,407222,100070405
    Gene Symbol and SynonymsSIAT7-F,SIAT7F,st6GalNAc-VI,ST6GALNAC6,ST6GALNACVI
    Uniprot AccessionQ969X2,Q08E15
    Uniprot Entry NameSIA7F_HUMAN,SIA7F_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000160408
    Target ClassificationN/A

    The target: ST6GALNAC6, gene name: ST6GALNAC6, also named as SIAT7-F, SIAT7F, ST6GALNACVI. ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.