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Anti-STOM/ BND7/ EPB7 monoclonal antibody
Anti-STOM/ BND7/ EPB7 antibody for FACS & in-vivo assay
Go to STOM/STOM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1719-Ab-1/ GM-Tg-hg-MP1719-Ab-2 | Anti-Human STOM monoclonal antibody | Human |
| GM-Tg-rg-MP1719-Ab-1/ GM-Tg-rg-MP1719-Ab-2 | Anti-Rat STOM monoclonal antibody | Rat |
| GM-Tg-mg-MP1719-Ab-1/ GM-Tg-mg-MP1719-Ab-2 | Anti-Mouse STOM monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1719-Ab-1/ GM-Tg-cynog-MP1719-Ab-2 | Anti-Cynomolgus/ Rhesus macaque STOM monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1719-Ab-1/ GM-Tg-felg-MP1719-Ab-2 | Anti-Feline STOM monoclonal antibody | Feline |
| GM-Tg-cang-MP1719-Ab-1/ GM-Tg-cang-MP1719-Ab-2 | Anti-Canine STOM monoclonal antibody | Canine |
| GM-Tg-bovg-MP1719-Ab-1/ GM-Tg-bovg-MP1719-Ab-2 | Anti-Bovine STOM monoclonal antibody | Bovine |
| GM-Tg-equg-MP1719-Ab-1/ GM-Tg-equg-MP1719-Ab-2 | Anti-Equine STOM monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1719-Ab-1/ GM-Tg-hg-MP1719-Ab-2; GM-Tg-rg-MP1719-Ab-1/ GM-Tg-rg-MP1719-Ab-2; GM-Tg-mg-MP1719-Ab-1/ GM-Tg-mg-MP1719-Ab-2; GM-Tg-cynog-MP1719-Ab-1/ GM-Tg-cynog-MP1719-Ab-2; GM-Tg-felg-MP1719-Ab-1/ GM-Tg-felg-MP1719-Ab-2; GM-Tg-cang-MP1719-Ab-1/ GM-Tg-cang-MP1719-Ab-2; GM-Tg-bovg-MP1719-Ab-1/ GM-Tg-bovg-MP1719-Ab-2; GM-Tg-equg-MP1719-Ab-1/ GM-Tg-equg-MP1719-Ab-2 |
| Products Name | Anti-STOM monoclonal antibody |
| Format | mab |
| Target Name | STOM |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-STOM benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species STOM/ BND7/ EPB7 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003512 | human STOM Lentivirus particle |
| ORF Viral Vector | vGMLP004029 | human STOM Lentivirus particle |
| ORF Viral Vector | pGMLP004029 | human STOM Lentivirus plasmid |
| ORF Viral Vector | pGMLP003512 | human STOM Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000843 | mouse Stom Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000843 | mouse Stom Lentivirus particle |
Target information
| Target ID | GM-MP1719 |
| Target Name | STOM |
| Gene ID | 2040,13830,296655,699584,612719,101088627,100125834,100071711 |
| Gene Symbol and Synonyms | BND7,EPB7,Epb7.2,EPB72,STOM |
| Uniprot Accession | P27105 |
| Uniprot Entry Name | STOM_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000148175 |
| Target Classification | N/A |
The target: STOM, gene name: STOM, also named as BND7, EPB7, EPB72. This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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