Anti-STX6 monoclonal antibody

Anti-STX6 antibody for FACS & in-vivo assay

Target products collectionGo to STX6/STX6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1729-Ab-1/ GM-Tg-hg-MP1729-Ab-2Anti-Human STX6 monoclonal antibodyHuman
GM-Tg-rg-MP1729-Ab-1/ GM-Tg-rg-MP1729-Ab-2Anti-Rat STX6 monoclonal antibodyRat
GM-Tg-mg-MP1729-Ab-1/ GM-Tg-mg-MP1729-Ab-2Anti-Mouse STX6 monoclonal antibodyMouse
GM-Tg-cynog-MP1729-Ab-1/ GM-Tg-cynog-MP1729-Ab-2Anti-Cynomolgus/ Rhesus macaque STX6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1729-Ab-1/ GM-Tg-felg-MP1729-Ab-2Anti-Feline STX6 monoclonal antibodyFeline
GM-Tg-cang-MP1729-Ab-1/ GM-Tg-cang-MP1729-Ab-2Anti-Canine STX6 monoclonal antibodyCanine
GM-Tg-bovg-MP1729-Ab-1/ GM-Tg-bovg-MP1729-Ab-2Anti-Bovine STX6 monoclonal antibodyBovine
GM-Tg-equg-MP1729-Ab-1/ GM-Tg-equg-MP1729-Ab-2Anti-Equine STX6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1729-Ab-1/ GM-Tg-hg-MP1729-Ab-2; GM-Tg-rg-MP1729-Ab-1/ GM-Tg-rg-MP1729-Ab-2;
GM-Tg-mg-MP1729-Ab-1/ GM-Tg-mg-MP1729-Ab-2; GM-Tg-cynog-MP1729-Ab-1/ GM-Tg-cynog-MP1729-Ab-2;
GM-Tg-felg-MP1729-Ab-1/ GM-Tg-felg-MP1729-Ab-2; GM-Tg-cang-MP1729-Ab-1/ GM-Tg-cang-MP1729-Ab-2;
GM-Tg-bovg-MP1729-Ab-1/ GM-Tg-bovg-MP1729-Ab-2; GM-Tg-equg-MP1729-Ab-1/ GM-Tg-equg-MP1729-Ab-2
Products NameAnti-STX6 monoclonal antibody
Formatmab
Target NameSTX6
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-STX6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species STX6 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1729
    Target NameSTX6
    Gene ID10228,58244,60562,716157,490303,101094565,510909,100054016
    Gene Symbol and Synonyms2310039E05Rik,2410005I16Rik,STX6,syntaxin-6
    Uniprot AccessionO43752,Q63635
    Uniprot Entry NameSTX6_HUMAN,STX6_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000135823
    Target ClassificationN/A

    The target: STX6, gene name: STX6, also named as . Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome; perinuclear region of cytoplasm; and trans-Golgi network. Part of SNARE complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.