Anti-SNG1/ SYNGR1 monoclonal antibody

Anti-SNG1/ SYNGR1 antibody for FACS & in-vivo assay

Target products collectionGo to SYNGR1/SYNGR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1737-Ab-1/ GM-Tg-hg-MP1737-Ab-2Anti-Human SYNGR1 monoclonal antibodyHuman
GM-Tg-rg-MP1737-Ab-1/ GM-Tg-rg-MP1737-Ab-2Anti-Rat SYNGR1 monoclonal antibodyRat
GM-Tg-mg-MP1737-Ab-1/ GM-Tg-mg-MP1737-Ab-2Anti-Mouse SYNGR1 monoclonal antibodyMouse
GM-Tg-cynog-MP1737-Ab-1/ GM-Tg-cynog-MP1737-Ab-2Anti-Cynomolgus/ Rhesus macaque SYNGR1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1737-Ab-1/ GM-Tg-felg-MP1737-Ab-2Anti-Feline SYNGR1 monoclonal antibodyFeline
GM-Tg-cang-MP1737-Ab-1/ GM-Tg-cang-MP1737-Ab-2Anti-Canine SYNGR1 monoclonal antibodyCanine
GM-Tg-bovg-MP1737-Ab-1/ GM-Tg-bovg-MP1737-Ab-2Anti-Bovine SYNGR1 monoclonal antibodyBovine
GM-Tg-equg-MP1737-Ab-1/ GM-Tg-equg-MP1737-Ab-2Anti-Equine SYNGR1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1737-Ab-1/ GM-Tg-hg-MP1737-Ab-2; GM-Tg-rg-MP1737-Ab-1/ GM-Tg-rg-MP1737-Ab-2;
GM-Tg-mg-MP1737-Ab-1/ GM-Tg-mg-MP1737-Ab-2; GM-Tg-cynog-MP1737-Ab-1/ GM-Tg-cynog-MP1737-Ab-2;
GM-Tg-felg-MP1737-Ab-1/ GM-Tg-felg-MP1737-Ab-2; GM-Tg-cang-MP1737-Ab-1/ GM-Tg-cang-MP1737-Ab-2;
GM-Tg-bovg-MP1737-Ab-1/ GM-Tg-bovg-MP1737-Ab-2; GM-Tg-equg-MP1737-Ab-1/ GM-Tg-equg-MP1737-Ab-2
Products NameAnti-SYNGR1 monoclonal antibody
Formatmab
Target NameSYNGR1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SYNGR1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SNG1/ SYNGR1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1737
    Target NameSYNGR1
    Gene ID9145,20972,29205,100427479,106559395,101096580,534995,102150091
    Gene Symbol and Synonymsp29,SYNGR1,Syngr1b
    Uniprot AccessionO43759,Q62876
    Uniprot Entry NameSNG1_HUMAN,SNG1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000100321
    Target ClassificationN/A

    The target: SYNGR1, gene name: SYNGR1, also named as . This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.