Anti-TA2R1/ TAS2R1/ T2R1 monoclonal antibody

Anti-TA2R1/ TAS2R1/ T2R1 antibody for FACS & in-vivo assay

Target products collectionGo to TAS2R1/TAS2R1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1759-Ab-1/ GM-Tg-hg-MP1759-Ab-2Anti-Human TAS2R1 monoclonal antibodyHuman
GM-Tg-rg-MP1759-Ab-1/ GM-Tg-rg-MP1759-Ab-2Anti-Rat TAS2R1 monoclonal antibodyRat
GM-Tg-mg-MP1759-Ab-1/ GM-Tg-mg-MP1759-Ab-2Anti-Mouse TAS2R1 monoclonal antibodyMouse
GM-Tg-cynog-MP1759-Ab-1/ GM-Tg-cynog-MP1759-Ab-2Anti-Cynomolgus/ Rhesus macaque TAS2R1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1759-Ab-1/ GM-Tg-felg-MP1759-Ab-2Anti-Feline TAS2R1 monoclonal antibodyFeline
GM-Tg-cang-MP1759-Ab-1/ GM-Tg-cang-MP1759-Ab-2Anti-Canine TAS2R1 monoclonal antibodyCanine
GM-Tg-bovg-MP1759-Ab-1/ GM-Tg-bovg-MP1759-Ab-2Anti-Bovine TAS2R1 monoclonal antibodyBovine
GM-Tg-equg-MP1759-Ab-1/ GM-Tg-equg-MP1759-Ab-2Anti-Equine TAS2R1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1759-Ab-1/ GM-Tg-hg-MP1759-Ab-2; GM-Tg-rg-MP1759-Ab-1/ GM-Tg-rg-MP1759-Ab-2;
GM-Tg-mg-MP1759-Ab-1/ GM-Tg-mg-MP1759-Ab-2; GM-Tg-cynog-MP1759-Ab-1/ GM-Tg-cynog-MP1759-Ab-2;
GM-Tg-felg-MP1759-Ab-1/ GM-Tg-felg-MP1759-Ab-2; GM-Tg-cang-MP1759-Ab-1/ GM-Tg-cang-MP1759-Ab-2;
GM-Tg-bovg-MP1759-Ab-1/ GM-Tg-bovg-MP1759-Ab-2; GM-Tg-equg-MP1759-Ab-1/ GM-Tg-equg-MP1759-Ab-2
Products NameAnti-TAS2R1 monoclonal antibody
Formatmab
Target NameTAS2R1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TAS2R1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TA2R1/ TAS2R1/ T2R1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1759
    Target NameTAS2R1
    Gene ID50834,57254,78979,696264,100271742,101093835,664649,100054561
    Gene Symbol and SynonymsCAFA-T2R1,mGR19,mt2r19,T2R1,T2r19,TAS2R1,Tas2r119,Tas2r19,TRB7
    Uniprot AccessionQ9NYW7,Q9JKU1
    Uniprot Entry NameTA2R1_HUMAN,TR119_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169777
    Target ClassificationGPCR

    The target: TAS2R1, gene name: TAS2R1, also named as T2R1, TRB7. This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.