Anti-T2R40/ TAS2R40/ GPR60 monoclonal antibody

Anti-T2R40/ TAS2R40/ GPR60 antibody for FACS & in-vivo assay

Target products collectionGo to TAS2R40/TAS2R40 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1770-Ab-1/ GM-Tg-hg-MP1770-Ab-2Anti-Human TAS2R40 monoclonal antibodyHuman
GM-Tg-rg-MP1770-Ab-1/ GM-Tg-rg-MP1770-Ab-2Anti-Rat TAS2R40 monoclonal antibodyRat
GM-Tg-mg-MP1770-Ab-1/ GM-Tg-mg-MP1770-Ab-2Anti-Mouse TAS2R40 monoclonal antibodyMouse
GM-Tg-cynog-MP1770-Ab-1/ GM-Tg-cynog-MP1770-Ab-2Anti-Cynomolgus/ Rhesus macaque TAS2R40 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1770-Ab-1/ GM-Tg-felg-MP1770-Ab-2Anti-Feline TAS2R40 monoclonal antibodyFeline
GM-Tg-cang-MP1770-Ab-1/ GM-Tg-cang-MP1770-Ab-2Anti-Canine TAS2R40 monoclonal antibodyCanine
GM-Tg-bovg-MP1770-Ab-1/ GM-Tg-bovg-MP1770-Ab-2Anti-Bovine TAS2R40 monoclonal antibodyBovine
GM-Tg-equg-MP1770-Ab-1/ GM-Tg-equg-MP1770-Ab-2Anti-Equine TAS2R40 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1770-Ab-1/ GM-Tg-hg-MP1770-Ab-2; GM-Tg-rg-MP1770-Ab-1/ GM-Tg-rg-MP1770-Ab-2;
GM-Tg-mg-MP1770-Ab-1/ GM-Tg-mg-MP1770-Ab-2; GM-Tg-cynog-MP1770-Ab-1/ GM-Tg-cynog-MP1770-Ab-2;
GM-Tg-felg-MP1770-Ab-1/ GM-Tg-felg-MP1770-Ab-2; GM-Tg-cang-MP1770-Ab-1/ GM-Tg-cang-MP1770-Ab-2;
GM-Tg-bovg-MP1770-Ab-1/ GM-Tg-bovg-MP1770-Ab-2; GM-Tg-equg-MP1770-Ab-1/ GM-Tg-equg-MP1770-Ab-2
Products NameAnti-TAS2R40 monoclonal antibody
Formatmab
Target NameTAS2R40
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TAS2R40 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species T2R40/ TAS2R40/ GPR60 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1770
    Target NameTAS2R40
    Gene ID259286,387515,500101,706077,101087467,785133,100050534
    Gene Symbol and SynonymsGPR60,mt2r33,RGD1562314,T2R40,T2R58,Tas2r144,TAS2R40,Tas2r44
    Uniprot AccessionP59535,Q67ET2
    Uniprot Entry NameT2R40_HUMAN,T2R40_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000221937
    Target ClassificationGPCR

    The target: TAS2R40, gene name: TAS2R40, also named as GPR60, T2R40, T2R58. This gene encodes a member of the bitter taste receptor family which belong to the G protein-coupled receptor superfamily and are predominantly expressed in taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a seven-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered together with eight other taste receptor genes on chromosome 7. A decrease in the expression of this gene is associated with hypogeusia. [provided by RefSeq, Jul 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.