Anti-T2R42/ TAS2R42/ T2R24 monoclonal antibody

Anti-T2R42/ TAS2R42/ T2R24 antibody for FACS & in-vivo assay

Target products collectionGo to TAS2R42/TAS2R42 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1773-Ab-1/ GM-Tg-hg-MP1773-Ab-2Anti-Human TAS2R42 monoclonal antibodyHuman
GM-Tg-rg-MP1773-Ab-1/ GM-Tg-rg-MP1773-Ab-2Anti-Rat TAS2R42 monoclonal antibodyRat
GM-Tg-mg-MP1773-Ab-1/ GM-Tg-mg-MP1773-Ab-2Anti-Mouse TAS2R42 monoclonal antibodyMouse
GM-Tg-cynog-MP1773-Ab-1/ GM-Tg-cynog-MP1773-Ab-2Anti-Cynomolgus/ Rhesus macaque TAS2R42 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1773-Ab-1/ GM-Tg-felg-MP1773-Ab-2Anti-Feline TAS2R42 monoclonal antibodyFeline
GM-Tg-cang-MP1773-Ab-1/ GM-Tg-cang-MP1773-Ab-2Anti-Canine TAS2R42 monoclonal antibodyCanine
GM-Tg-bovg-MP1773-Ab-1/ GM-Tg-bovg-MP1773-Ab-2Anti-Bovine TAS2R42 monoclonal antibodyBovine
GM-Tg-equg-MP1773-Ab-1/ GM-Tg-equg-MP1773-Ab-2Anti-Equine TAS2R42 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1773-Ab-1/ GM-Tg-hg-MP1773-Ab-2; GM-Tg-rg-MP1773-Ab-1/ GM-Tg-rg-MP1773-Ab-2;
GM-Tg-mg-MP1773-Ab-1/ GM-Tg-mg-MP1773-Ab-2; GM-Tg-cynog-MP1773-Ab-1/ GM-Tg-cynog-MP1773-Ab-2;
GM-Tg-felg-MP1773-Ab-1/ GM-Tg-felg-MP1773-Ab-2; GM-Tg-cang-MP1773-Ab-1/ GM-Tg-cang-MP1773-Ab-2;
GM-Tg-bovg-MP1773-Ab-1/ GM-Tg-bovg-MP1773-Ab-2; GM-Tg-equg-MP1773-Ab-1/ GM-Tg-equg-MP1773-Ab-2
Products NameAnti-TAS2R42 monoclonal antibody
Formatmab
Target NameTAS2R42
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TAS2R42 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species T2R42/ TAS2R42/ T2R24 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1773
    Target NameTAS2R42
    Gene ID353164,387356,100363053,695053,106783265
    Gene Symbol and SynonymsMamu-T2R55,mGR31,mt2r61,T2R24,T2R31,T2R42,T2R55,Tas2r131,Tas2r145,Tas2r31,TAS2R42,TAS2R55
    Uniprot AccessionQ7RTR8,Q645T9
    Uniprot Entry NameT2R42_HUMAN,T2R42_MACMU
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000186136
    Target ClassificationGPCR

    The target: TAS2R42, gene name: TAS2R42, also named as T2R24, T2R42, T2R55, TAS2R55. Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of taste. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.