Anti-T2R50/ TAS2R50/ T2R51 monoclonal antibody

Anti-T2R50/ TAS2R50/ T2R51 antibody for FACS & in-vivo assay

Target products collectionGo to TAS2R50/TAS2R50 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1776-Ab-1/ GM-Tg-hg-MP1776-Ab-2Anti-Human TAS2R50 monoclonal antibodyHuman
GM-Tg-rg-MP1776-Ab-1/ GM-Tg-rg-MP1776-Ab-2Anti-Rat TAS2R50 monoclonal antibodyRat
GM-Tg-mg-MP1776-Ab-1/ GM-Tg-mg-MP1776-Ab-2Anti-Mouse TAS2R50 monoclonal antibodyMouse
GM-Tg-cynog-MP1776-Ab-1/ GM-Tg-cynog-MP1776-Ab-2Anti-Cynomolgus/ Rhesus macaque TAS2R50 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1776-Ab-1/ GM-Tg-felg-MP1776-Ab-2Anti-Feline TAS2R50 monoclonal antibodyFeline
GM-Tg-cang-MP1776-Ab-1/ GM-Tg-cang-MP1776-Ab-2Anti-Canine TAS2R50 monoclonal antibodyCanine
GM-Tg-bovg-MP1776-Ab-1/ GM-Tg-bovg-MP1776-Ab-2Anti-Bovine TAS2R50 monoclonal antibodyBovine
GM-Tg-equg-MP1776-Ab-1/ GM-Tg-equg-MP1776-Ab-2Anti-Equine TAS2R50 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1776-Ab-1/ GM-Tg-hg-MP1776-Ab-2; GM-Tg-rg-MP1776-Ab-1/ GM-Tg-rg-MP1776-Ab-2;
GM-Tg-mg-MP1776-Ab-1/ GM-Tg-mg-MP1776-Ab-2; GM-Tg-cynog-MP1776-Ab-1/ GM-Tg-cynog-MP1776-Ab-2;
GM-Tg-felg-MP1776-Ab-1/ GM-Tg-felg-MP1776-Ab-2; GM-Tg-cang-MP1776-Ab-1/ GM-Tg-cang-MP1776-Ab-2;
GM-Tg-bovg-MP1776-Ab-1/ GM-Tg-bovg-MP1776-Ab-2; GM-Tg-equg-MP1776-Ab-1/ GM-Tg-equg-MP1776-Ab-2
Products NameAnti-TAS2R50 monoclonal antibody
Formatmab
Target NameTAS2R50
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TAS2R50 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species T2R50/ TAS2R50/ T2R51 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1776
    Target NameTAS2R50
    Gene ID259296
    Gene Symbol and SynonymsT2R50,T2R51,TAS2R50,TAS2R51
    Uniprot AccessionP59544
    Uniprot Entry NameT2R50_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000212126
    Target ClassificationGPCR

    The target: TAS2R50, gene name: TAS2R50, also named as T2R50, T2R51, TAS2R51. TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). See also TAS2R10 (MIM 604791).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.