Anti-TX101/ TEX101/ CT131 monoclonal antibody

Anti-TX101/ TEX101/ CT131 antibody for FACS & in-vivo assay

Target products collectionGo to TEX101/TEX101 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1791-Ab-1/ GM-Tg-hg-MP1791-Ab-2Anti-Human TEX101 monoclonal antibodyHuman
GM-Tg-rg-MP1791-Ab-1/ GM-Tg-rg-MP1791-Ab-2Anti-Rat TEX101 monoclonal antibodyRat
GM-Tg-mg-MP1791-Ab-1/ GM-Tg-mg-MP1791-Ab-2Anti-Mouse TEX101 monoclonal antibodyMouse
GM-Tg-cynog-MP1791-Ab-1/ GM-Tg-cynog-MP1791-Ab-2Anti-Cynomolgus/ Rhesus macaque TEX101 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1791-Ab-1/ GM-Tg-felg-MP1791-Ab-2Anti-Feline TEX101 monoclonal antibodyFeline
GM-Tg-cang-MP1791-Ab-1/ GM-Tg-cang-MP1791-Ab-2Anti-Canine TEX101 monoclonal antibodyCanine
GM-Tg-bovg-MP1791-Ab-1/ GM-Tg-bovg-MP1791-Ab-2Anti-Bovine TEX101 monoclonal antibodyBovine
GM-Tg-equg-MP1791-Ab-1/ GM-Tg-equg-MP1791-Ab-2Anti-Equine TEX101 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1791-Ab-1/ GM-Tg-hg-MP1791-Ab-2; GM-Tg-rg-MP1791-Ab-1/ GM-Tg-rg-MP1791-Ab-2;
GM-Tg-mg-MP1791-Ab-1/ GM-Tg-mg-MP1791-Ab-2; GM-Tg-cynog-MP1791-Ab-1/ GM-Tg-cynog-MP1791-Ab-2;
GM-Tg-felg-MP1791-Ab-1/ GM-Tg-felg-MP1791-Ab-2; GM-Tg-cang-MP1791-Ab-1/ GM-Tg-cang-MP1791-Ab-2;
GM-Tg-bovg-MP1791-Ab-1/ GM-Tg-bovg-MP1791-Ab-2; GM-Tg-equg-MP1791-Ab-1/ GM-Tg-equg-MP1791-Ab-2
Products NameAnti-TEX101 monoclonal antibody
Formatmab
Target NameTEX101
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TEX101 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TX101/ TEX101/ CT131 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1791
    Target NameTEX101
    Gene ID83639,56746,207113,711375,612423,101081590,616282,100070041
    Gene Symbol and Synonyms1700008H15Rik,CT131,GTPR867,NYD-SP8,PRO1884,SGRG,SPATA44,Tec21,TES101RP,TEX101
    Uniprot AccessionQ9BY14,Q924B5
    Uniprot Entry NameTX101_HUMAN,TX101_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000131126
    Target ClassificationN/A

    The target: TEX101, gene name: TEX101, also named as CT131, GTPR867, NYD-SP8, PRO1884, SGRG, SPATA44, TES101RP. Predicted to be involved in binding activity of sperm to zona pellucida; flagellated sperm motility; and regulation of flagellated sperm motility. Predicted to be located in acrosomal vesicle; extracellular region; and plasma membrane. Predicted to be active in plasma membrane raft. Predicted to be anchored component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.