Anti-TGON2/ TGOLN2/ TGN38 monoclonal antibody

Anti-TGON2/ TGOLN2/ TGN38 antibody for FACS & in-vivo assay

Target products collectionGo to TGOLN2/TGOLN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1794-Ab-1/ GM-Tg-hg-MP1794-Ab-2Anti-Human TGOLN2 monoclonal antibodyHuman
GM-Tg-rg-MP1794-Ab-1/ GM-Tg-rg-MP1794-Ab-2Anti-Rat TGOLN2 monoclonal antibodyRat
GM-Tg-mg-MP1794-Ab-1/ GM-Tg-mg-MP1794-Ab-2Anti-Mouse TGOLN2 monoclonal antibodyMouse
GM-Tg-cynog-MP1794-Ab-1/ GM-Tg-cynog-MP1794-Ab-2Anti-Cynomolgus/ Rhesus macaque TGOLN2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1794-Ab-1/ GM-Tg-felg-MP1794-Ab-2Anti-Feline TGOLN2 monoclonal antibodyFeline
GM-Tg-cang-MP1794-Ab-1/ GM-Tg-cang-MP1794-Ab-2Anti-Canine TGOLN2 monoclonal antibodyCanine
GM-Tg-bovg-MP1794-Ab-1/ GM-Tg-bovg-MP1794-Ab-2Anti-Bovine TGOLN2 monoclonal antibodyBovine
GM-Tg-equg-MP1794-Ab-1/ GM-Tg-equg-MP1794-Ab-2Anti-Equine TGOLN2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1794-Ab-1/ GM-Tg-hg-MP1794-Ab-2; GM-Tg-rg-MP1794-Ab-1/ GM-Tg-rg-MP1794-Ab-2;
GM-Tg-mg-MP1794-Ab-1/ GM-Tg-mg-MP1794-Ab-2; GM-Tg-cynog-MP1794-Ab-1/ GM-Tg-cynog-MP1794-Ab-2;
GM-Tg-felg-MP1794-Ab-1/ GM-Tg-felg-MP1794-Ab-2; GM-Tg-cang-MP1794-Ab-1/ GM-Tg-cang-MP1794-Ab-2;
GM-Tg-bovg-MP1794-Ab-1/ GM-Tg-bovg-MP1794-Ab-2; GM-Tg-equg-MP1794-Ab-1/ GM-Tg-equg-MP1794-Ab-2
Products NameAnti-TGOLN2 monoclonal antibody
Formatmab
Target NameTGOLN2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TGOLN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TGON2/ TGOLN2/ TGN38 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1794
    Target NameTGOLN2
    Gene ID10618,22135,192152,100426141,475772,105259637,511904,100067403
    Gene Symbol and SynonymshTGN46,hTGN48,hTGN51,TGN38,TGN38B,TGN41,TGN46,TGN48,TGN51,Tgoln1,TGOLN2,Ttgn1,TTGN2
    Uniprot AccessionO43493,P19814
    Uniprot Entry NameTGON2_HUMAN,TGON3_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000152291
    Target ClassificationN/A

    The target: TGOLN2, gene name: TGOLN2, also named as TGN38, TGN46, TGN48, TGN51, TTGN2. This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.