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Anti-THY1/ CD90/ CDw90 monoclonal antibody
Anti-THY1/ CD90/ CDw90 antibody for FACS & in-vivo assay
Go to THY1/THY1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1797-Ab-1/ GM-Tg-hg-MP1797-Ab-2 | Anti-Human THY1 monoclonal antibody | Human |
| GM-Tg-rg-MP1797-Ab-1/ GM-Tg-rg-MP1797-Ab-2 | Anti-Rat THY1 monoclonal antibody | Rat |
| GM-Tg-mg-MP1797-Ab-1/ GM-Tg-mg-MP1797-Ab-2 | Anti-Mouse THY1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1797-Ab-1/ GM-Tg-cynog-MP1797-Ab-2 | Anti-Cynomolgus/ Rhesus macaque THY1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1797-Ab-1/ GM-Tg-felg-MP1797-Ab-2 | Anti-Feline THY1 monoclonal antibody | Feline |
| GM-Tg-cang-MP1797-Ab-1/ GM-Tg-cang-MP1797-Ab-2 | Anti-Canine THY1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1797-Ab-1/ GM-Tg-bovg-MP1797-Ab-2 | Anti-Bovine THY1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1797-Ab-1/ GM-Tg-equg-MP1797-Ab-2 | Anti-Equine THY1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1797-Ab-1/ GM-Tg-hg-MP1797-Ab-2; GM-Tg-rg-MP1797-Ab-1/ GM-Tg-rg-MP1797-Ab-2; GM-Tg-mg-MP1797-Ab-1/ GM-Tg-mg-MP1797-Ab-2; GM-Tg-cynog-MP1797-Ab-1/ GM-Tg-cynog-MP1797-Ab-2; GM-Tg-felg-MP1797-Ab-1/ GM-Tg-felg-MP1797-Ab-2; GM-Tg-cang-MP1797-Ab-1/ GM-Tg-cang-MP1797-Ab-2; GM-Tg-bovg-MP1797-Ab-1/ GM-Tg-bovg-MP1797-Ab-2; GM-Tg-equg-MP1797-Ab-1/ GM-Tg-equg-MP1797-Ab-2 |
| Products Name | Anti-THY1 monoclonal antibody |
| Format | mab |
| Target Name | THY1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-THY1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species THY1/ CD90/ CDw90 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP002825 | human THY1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002825 | human THY1 Lentivirus particle |
| ORF Viral Vector | pGMLPm000568 | mouse Thy1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000568 | mouse Thy1 Lentivirus particle |
Target information
| Target ID | GM-MP1797 |
| Target Name | THY1 |
| Gene ID | 7070,21838,24832,705321,489365,101098005,614712,100063377 |
| Gene Symbol and Synonyms | CD7,CD90,CDw90,T25,Thy-1,Thy-1.2,THY1,Thy1.1,Thy1.2 |
| Uniprot Accession | P04216,P01830,O62643 |
| Uniprot Entry Name | THY1_HUMAN,THY1_MACMU,THY1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Prostate Cancer, Malignant neoplasm of prostate |
| Gene Ensembl | ENSG00000154096 |
| Target Classification | N/A |
The target: THY1, gene name: THY1, also named as CD90, CDw90. This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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