Anti-TEFF1/ ™EFF1/ C9orf2 monoclonal antibody

Anti-TEFF1/ ™EFF1/ C9orf2 antibody for FACS & in-vivo assay

Target products collectionGo to ™EFF1/™EFF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1809-Ab-1/ GM-Tg-hg-MP1809-Ab-2Anti-Human ™EFF1 monoclonal antibodyHuman
GM-Tg-rg-MP1809-Ab-1/ GM-Tg-rg-MP1809-Ab-2Anti-Rat ™EFF1 monoclonal antibodyRat
GM-Tg-mg-MP1809-Ab-1/ GM-Tg-mg-MP1809-Ab-2Anti-Mouse ™EFF1 monoclonal antibodyMouse
GM-Tg-cynog-MP1809-Ab-1/ GM-Tg-cynog-MP1809-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EFF1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1809-Ab-1/ GM-Tg-felg-MP1809-Ab-2Anti-Feline ™EFF1 monoclonal antibodyFeline
GM-Tg-cang-MP1809-Ab-1/ GM-Tg-cang-MP1809-Ab-2Anti-Canine ™EFF1 monoclonal antibodyCanine
GM-Tg-bovg-MP1809-Ab-1/ GM-Tg-bovg-MP1809-Ab-2Anti-Bovine ™EFF1 monoclonal antibodyBovine
GM-Tg-equg-MP1809-Ab-1/ GM-Tg-equg-MP1809-Ab-2Anti-Equine ™EFF1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1809-Ab-1/ GM-Tg-hg-MP1809-Ab-2; GM-Tg-rg-MP1809-Ab-1/ GM-Tg-rg-MP1809-Ab-2;
GM-Tg-mg-MP1809-Ab-1/ GM-Tg-mg-MP1809-Ab-2; GM-Tg-cynog-MP1809-Ab-1/ GM-Tg-cynog-MP1809-Ab-2;
GM-Tg-felg-MP1809-Ab-1/ GM-Tg-felg-MP1809-Ab-2; GM-Tg-cang-MP1809-Ab-1/ GM-Tg-cang-MP1809-Ab-2;
GM-Tg-bovg-MP1809-Ab-1/ GM-Tg-bovg-MP1809-Ab-2; GM-Tg-equg-MP1809-Ab-1/ GM-Tg-equg-MP1809-Ab-2
Products NameAnti-™EFF1 monoclonal antibody
Formatmab
Target Name™EFF1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™EFF1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TEFF1/ ™EFF1/ C9orf2 VLP (virus-like particle) (Products Developing)
    CytokineGM-Tg-g-MP1809-Ag-1transmembrane protein with EGF-like and two follistatin-like domains 1 (™EFF1) protein


    Target information

    Target IDGM-MP1809
    Target Name™EFF1
    Gene ID8577,230157,63845,714325,612942,101085756,100139803,102147843
    Gene Symbol and SynonymsA830033E11,C9orf2,CT120.1,H7365,M7365,™EFF1,TR-1,Tr1
    Uniprot AccessionQ8IYR6,Q9QYV1
    Uniprot Entry NameTEFF1_HUMAN,TEFF1_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000241697
    Target ClassificationN/A

    The target: ™EFF1, gene name: ™EFF1, also named as C9orf2, CT120.1, H7365, TR-1. Predicted to enable signaling receptor binding activity. Predicted to be involved in animal organ morphogenesis; neuron projection development; and tissue development. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.