Anti-™102/ ™EM102/ CBAP monoclonal antibody

Anti-™102/ ™EM102/ CBAP antibody for FACS & in-vivo assay

Target products collectionGo to ™EM102/™EM102 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1812-Ab-1/ GM-Tg-hg-MP1812-Ab-2Anti-Human ™EM102 monoclonal antibodyHuman
GM-Tg-rg-MP1812-Ab-1/ GM-Tg-rg-MP1812-Ab-2Anti-Rat ™EM102 monoclonal antibodyRat
GM-Tg-mg-MP1812-Ab-1/ GM-Tg-mg-MP1812-Ab-2Anti-Mouse ™EM102 monoclonal antibodyMouse
GM-Tg-cynog-MP1812-Ab-1/ GM-Tg-cynog-MP1812-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM102 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1812-Ab-1/ GM-Tg-felg-MP1812-Ab-2Anti-Feline ™EM102 monoclonal antibodyFeline
GM-Tg-cang-MP1812-Ab-1/ GM-Tg-cang-MP1812-Ab-2Anti-Canine ™EM102 monoclonal antibodyCanine
GM-Tg-bovg-MP1812-Ab-1/ GM-Tg-bovg-MP1812-Ab-2Anti-Bovine ™EM102 monoclonal antibodyBovine
GM-Tg-equg-MP1812-Ab-1/ GM-Tg-equg-MP1812-Ab-2Anti-Equine ™EM102 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1812-Ab-1/ GM-Tg-hg-MP1812-Ab-2; GM-Tg-rg-MP1812-Ab-1/ GM-Tg-rg-MP1812-Ab-2;
GM-Tg-mg-MP1812-Ab-1/ GM-Tg-mg-MP1812-Ab-2; GM-Tg-cynog-MP1812-Ab-1/ GM-Tg-cynog-MP1812-Ab-2;
GM-Tg-felg-MP1812-Ab-1/ GM-Tg-felg-MP1812-Ab-2; GM-Tg-cang-MP1812-Ab-1/ GM-Tg-cang-MP1812-Ab-2;
GM-Tg-bovg-MP1812-Ab-1/ GM-Tg-bovg-MP1812-Ab-2; GM-Tg-equg-MP1812-Ab-1/ GM-Tg-equg-MP1812-Ab-2
Products NameAnti-™EM102 monoclonal antibody
Formatmab
Target Name™EM102
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™EM102 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ™102/ ™EM102/ CBAP VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1812
    Target Name™EM102
    Gene ID284114,380705,497937,715461,111089959,101096929,508014,100061842
    Gene Symbol and Synonyms4632403M07Rik,CBAP,RGD1559450,™EM102,Tmem102-ps
    Uniprot AccessionQ8N9M5,Q1LZD1
    Uniprot Entry Name™102_HUMAN,™102_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000181284
    Target ClassificationN/A

    The target: ™EM102, gene name: ™EM102, also named as CBAP. Involved in regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; response to cytokine; and signal transduction. Acts upstream of or within positive regulation of T cell migration and positive regulation of cell adhesion. Located in cell surface. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.