Anti-T184A/ ™EM184A/ SDMG1 monoclonal antibody

Anti-T184A/ ™EM184A/ SDMG1 antibody for FACS & in-vivo assay

Target products collectionGo to ™EM184A/™EM184A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1825-Ab-1/ GM-Tg-hg-MP1825-Ab-2Anti-Human ™EM184A monoclonal antibodyHuman
GM-Tg-rg-MP1825-Ab-1/ GM-Tg-rg-MP1825-Ab-2Anti-Rat ™EM184A monoclonal antibodyRat
GM-Tg-mg-MP1825-Ab-1/ GM-Tg-mg-MP1825-Ab-2Anti-Mouse ™EM184A monoclonal antibodyMouse
GM-Tg-cynog-MP1825-Ab-1/ GM-Tg-cynog-MP1825-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM184A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1825-Ab-1/ GM-Tg-felg-MP1825-Ab-2Anti-Feline ™EM184A monoclonal antibodyFeline
GM-Tg-cang-MP1825-Ab-1/ GM-Tg-cang-MP1825-Ab-2Anti-Canine ™EM184A monoclonal antibodyCanine
GM-Tg-bovg-MP1825-Ab-1/ GM-Tg-bovg-MP1825-Ab-2Anti-Bovine ™EM184A monoclonal antibodyBovine
GM-Tg-equg-MP1825-Ab-1/ GM-Tg-equg-MP1825-Ab-2Anti-Equine ™EM184A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1825-Ab-1/ GM-Tg-hg-MP1825-Ab-2; GM-Tg-rg-MP1825-Ab-1/ GM-Tg-rg-MP1825-Ab-2;
GM-Tg-mg-MP1825-Ab-1/ GM-Tg-mg-MP1825-Ab-2; GM-Tg-cynog-MP1825-Ab-1/ GM-Tg-cynog-MP1825-Ab-2;
GM-Tg-felg-MP1825-Ab-1/ GM-Tg-felg-MP1825-Ab-2; GM-Tg-cang-MP1825-Ab-1/ GM-Tg-cang-MP1825-Ab-2;
GM-Tg-bovg-MP1825-Ab-1/ GM-Tg-bovg-MP1825-Ab-2; GM-Tg-equg-MP1825-Ab-1/ GM-Tg-equg-MP1825-Ab-2
Products NameAnti-™EM184A monoclonal antibody
Formatmab
Target Name™EM184A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™EM184A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species T184A/ ™EM184A/ SDMG1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1825
    Target Name™EM184A
    Gene ID202915,231832,304325,697461,100856376,101090068,524484,100053430
    Gene Symbol and SynonymsRGD1306702,SDMG1,™EM184A
    Uniprot AccessionQ6ZMB5,Q4QQS1,Q1RMW2
    Uniprot Entry NameT184A_HUMAN,T184A_RAT,T184A_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164855
    Target ClassificationN/A

    The target: ™EM184A, gene name: ™EM184A, also named as SDMG1. Predicted to enable heparin binding activity. Predicted to act upstream of or within germ-line sex determination; regulation of protein localization; and regulation of secretion. Predicted to be located in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Predicted to be active in early endosome membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.