- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-™M59/ ™EM59/ C1orf8 monoclonal antibody
Anti-™M59/ ™EM59/ C1orf8 antibody for FACS & in-vivo assay
Go to ™EM59/™EM59 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1836-Ab-1/ GM-Tg-hg-MP1836-Ab-2 | Anti-Human ™EM59 monoclonal antibody | Human |
| GM-Tg-rg-MP1836-Ab-1/ GM-Tg-rg-MP1836-Ab-2 | Anti-Rat ™EM59 monoclonal antibody | Rat |
| GM-Tg-mg-MP1836-Ab-1/ GM-Tg-mg-MP1836-Ab-2 | Anti-Mouse ™EM59 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1836-Ab-1/ GM-Tg-cynog-MP1836-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ™EM59 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1836-Ab-1/ GM-Tg-felg-MP1836-Ab-2 | Anti-Feline ™EM59 monoclonal antibody | Feline |
| GM-Tg-cang-MP1836-Ab-1/ GM-Tg-cang-MP1836-Ab-2 | Anti-Canine ™EM59 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1836-Ab-1/ GM-Tg-bovg-MP1836-Ab-2 | Anti-Bovine ™EM59 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1836-Ab-1/ GM-Tg-equg-MP1836-Ab-2 | Anti-Equine ™EM59 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1836-Ab-1/ GM-Tg-hg-MP1836-Ab-2; GM-Tg-rg-MP1836-Ab-1/ GM-Tg-rg-MP1836-Ab-2; GM-Tg-mg-MP1836-Ab-1/ GM-Tg-mg-MP1836-Ab-2; GM-Tg-cynog-MP1836-Ab-1/ GM-Tg-cynog-MP1836-Ab-2; GM-Tg-felg-MP1836-Ab-1/ GM-Tg-felg-MP1836-Ab-2; GM-Tg-cang-MP1836-Ab-1/ GM-Tg-cang-MP1836-Ab-2; GM-Tg-bovg-MP1836-Ab-1/ GM-Tg-bovg-MP1836-Ab-2; GM-Tg-equg-MP1836-Ab-1/ GM-Tg-equg-MP1836-Ab-2 |
| Products Name | Anti-™EM59 monoclonal antibody |
| Format | mab |
| Target Name | ™EM59 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-™EM59 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ™M59/ ™EM59/ C1orf8 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP002556 | human ™EM59 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002556 | human ™EM59 Lentivirus particle |
| ORF Viral Vector | pGMLPm002288 | mouse Tmem59 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002288 | mouse Tmem59 Lentivirus particle |
Target information
| Target ID | GM-MP1836 |
| Target Name | ™EM59 |
| Gene ID | 9528,56374,100196907,714942,479561,101096251,509775,100050223 |
| Gene Symbol and Synonyms | 1110001M20Rik,3110046P06Rik,C1orf8,D4Ertd20e,DCF1,HSPC001,MTDCF1,ORF18,PRO195,RGD1310313,Shd11,™EM59,UNQ169 |
| Uniprot Accession | Q9BXS4,Q3T0Q2 |
| Uniprot Entry Name | ™M59_HUMAN,™M59_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000116209 |
| Target Classification | N/A |
The target: ™EM59, gene name: ™EM59, also named as C1orf8, DCF1, HSPC001, PRO195, UNQ169. This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
