Anti-™M98/ ™EM98/ TADA1 monoclonal antibody

Anti-™M98/ ™EM98/ TADA1 antibody for FACS & in-vivo assay

Target products collectionGo to ™EM98/™EM98 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1845-Ab-1/ GM-Tg-hg-MP1845-Ab-2Anti-Human ™EM98 monoclonal antibodyHuman
GM-Tg-rg-MP1845-Ab-1/ GM-Tg-rg-MP1845-Ab-2Anti-Rat ™EM98 monoclonal antibodyRat
GM-Tg-mg-MP1845-Ab-1/ GM-Tg-mg-MP1845-Ab-2Anti-Mouse ™EM98 monoclonal antibodyMouse
GM-Tg-cynog-MP1845-Ab-1/ GM-Tg-cynog-MP1845-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM98 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1845-Ab-1/ GM-Tg-felg-MP1845-Ab-2Anti-Feline ™EM98 monoclonal antibodyFeline
GM-Tg-cang-MP1845-Ab-1/ GM-Tg-cang-MP1845-Ab-2Anti-Canine ™EM98 monoclonal antibodyCanine
GM-Tg-bovg-MP1845-Ab-1/ GM-Tg-bovg-MP1845-Ab-2Anti-Bovine ™EM98 monoclonal antibodyBovine
GM-Tg-equg-MP1845-Ab-1/ GM-Tg-equg-MP1845-Ab-2Anti-Equine ™EM98 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1845-Ab-1/ GM-Tg-hg-MP1845-Ab-2; GM-Tg-rg-MP1845-Ab-1/ GM-Tg-rg-MP1845-Ab-2;
GM-Tg-mg-MP1845-Ab-1/ GM-Tg-mg-MP1845-Ab-2; GM-Tg-cynog-MP1845-Ab-1/ GM-Tg-cynog-MP1845-Ab-2;
GM-Tg-felg-MP1845-Ab-1/ GM-Tg-felg-MP1845-Ab-2; GM-Tg-cang-MP1845-Ab-1/ GM-Tg-cang-MP1845-Ab-2;
GM-Tg-bovg-MP1845-Ab-1/ GM-Tg-bovg-MP1845-Ab-2; GM-Tg-equg-MP1845-Ab-1/ GM-Tg-equg-MP1845-Ab-2
Products NameAnti-™EM98 monoclonal antibody
Formatmab
Target Name™EM98
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™EM98 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ™M98/ ™EM98/ TADA1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1845
    Target Name™EM98
    Gene ID26022,103743,303356,718166,612961,101095697,513445,100071736
    Gene Symbol and Synonyms6530411B15Rik,Rwhs,TADA1,™EM98
    Uniprot AccessionQ9Y2Y6,Q6AYS5,Q2HJB9
    Uniprot Entry Name™M98_HUMAN,™M98_RAT,™M98_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000006042
    Target ClassificationN/A

    The target: ™EM98, gene name: ™EM98, also named as TADA1. This gene encodes a transmembrane protein. A missense mutation in this gene result in Nanophthalmos 4 (NNO4). Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.