Anti-™11B/ ™PRSS11B monoclonal antibody

Anti-™11B/ ™PRSS11B antibody for FACS & in-vivo assay

Target products collectionGo to ™PRSS11B/™PRSS11B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1848-Ab-1/ GM-Tg-hg-MP1848-Ab-2Anti-Human ™PRSS11B monoclonal antibodyHuman
GM-Tg-rg-MP1848-Ab-1/ GM-Tg-rg-MP1848-Ab-2Anti-Rat ™PRSS11B monoclonal antibodyRat
GM-Tg-mg-MP1848-Ab-1/ GM-Tg-mg-MP1848-Ab-2Anti-Mouse ™PRSS11B monoclonal antibodyMouse
GM-Tg-cynog-MP1848-Ab-1/ GM-Tg-cynog-MP1848-Ab-2Anti-Cynomolgus/ Rhesus macaque ™PRSS11B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1848-Ab-1/ GM-Tg-felg-MP1848-Ab-2Anti-Feline ™PRSS11B monoclonal antibodyFeline
GM-Tg-cang-MP1848-Ab-1/ GM-Tg-cang-MP1848-Ab-2Anti-Canine ™PRSS11B monoclonal antibodyCanine
GM-Tg-bovg-MP1848-Ab-1/ GM-Tg-bovg-MP1848-Ab-2Anti-Bovine ™PRSS11B monoclonal antibodyBovine
GM-Tg-equg-MP1848-Ab-1/ GM-Tg-equg-MP1848-Ab-2Anti-Equine ™PRSS11B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1848-Ab-1/ GM-Tg-hg-MP1848-Ab-2; GM-Tg-rg-MP1848-Ab-1/ GM-Tg-rg-MP1848-Ab-2;
GM-Tg-mg-MP1848-Ab-1/ GM-Tg-mg-MP1848-Ab-2; GM-Tg-cynog-MP1848-Ab-1/ GM-Tg-cynog-MP1848-Ab-2;
GM-Tg-felg-MP1848-Ab-1/ GM-Tg-felg-MP1848-Ab-2; GM-Tg-cang-MP1848-Ab-1/ GM-Tg-cang-MP1848-Ab-2;
GM-Tg-bovg-MP1848-Ab-1/ GM-Tg-bovg-MP1848-Ab-2; GM-Tg-equg-MP1848-Ab-1/ GM-Tg-equg-MP1848-Ab-2
Products NameAnti-™PRSS11B monoclonal antibody
Formatmab
Target Name™PRSS11B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™PRSS11B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ™11B/ ™PRSS11B VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP004319human ™PRSS11B Lentivirus particle
    ORF Viral VectorpGMLP004319human ™PRSS11B Lentivirus plasmid


    Target information

    Target IDGM-MP1848
    Target Name™PRSS11B
    Gene ID132724,365265,709809
    Gene Symbol and SynonymsHATL5,™PRSS11B,Tmprss11bnl
    Uniprot AccessionQ86T26,Q6IE14
    Uniprot Entry Name™11B_HUMAN,™11L_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000185873
    Target ClassificationN/A

    The target: ™PRSS11B, gene name: ™PRSS11B, also named as . Enables serine-type peptidase activity. Predicted to be involved in proteolysis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.