Anti-™11E/ ™PRSS11E/ DESC12 monoclonal antibody

Anti-™11E/ ™PRSS11E/ DESC12 antibody for FACS & in-vivo assay

Target products collectionGo to ™PRSS11E/™PRSS11E products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1849-Ab-1/ GM-Tg-hg-MP1849-Ab-2Anti-Human ™PRSS11E monoclonal antibodyHuman
GM-Tg-rg-MP1849-Ab-1/ GM-Tg-rg-MP1849-Ab-2Anti-Rat ™PRSS11E monoclonal antibodyRat
GM-Tg-mg-MP1849-Ab-1/ GM-Tg-mg-MP1849-Ab-2Anti-Mouse ™PRSS11E monoclonal antibodyMouse
GM-Tg-cynog-MP1849-Ab-1/ GM-Tg-cynog-MP1849-Ab-2Anti-Cynomolgus/ Rhesus macaque ™PRSS11E monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1849-Ab-1/ GM-Tg-felg-MP1849-Ab-2Anti-Feline ™PRSS11E monoclonal antibodyFeline
GM-Tg-cang-MP1849-Ab-1/ GM-Tg-cang-MP1849-Ab-2Anti-Canine ™PRSS11E monoclonal antibodyCanine
GM-Tg-bovg-MP1849-Ab-1/ GM-Tg-bovg-MP1849-Ab-2Anti-Bovine ™PRSS11E monoclonal antibodyBovine
GM-Tg-equg-MP1849-Ab-1/ GM-Tg-equg-MP1849-Ab-2Anti-Equine ™PRSS11E monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1849-Ab-1/ GM-Tg-hg-MP1849-Ab-2; GM-Tg-rg-MP1849-Ab-1/ GM-Tg-rg-MP1849-Ab-2;
GM-Tg-mg-MP1849-Ab-1/ GM-Tg-mg-MP1849-Ab-2; GM-Tg-cynog-MP1849-Ab-1/ GM-Tg-cynog-MP1849-Ab-2;
GM-Tg-felg-MP1849-Ab-1/ GM-Tg-felg-MP1849-Ab-2; GM-Tg-cang-MP1849-Ab-1/ GM-Tg-cang-MP1849-Ab-2;
GM-Tg-bovg-MP1849-Ab-1/ GM-Tg-bovg-MP1849-Ab-2; GM-Tg-equg-MP1849-Ab-1/ GM-Tg-equg-MP1849-Ab-2
Products NameAnti-™PRSS11E monoclonal antibody
Formatmab
Target Name™PRSS11E
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™PRSS11E benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ™11E/ ™PRSS11E/ DESC12 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP003059human ™PRSS11E Lentivirus plasmid
    ORF Viral VectorvGMLP003059human ™PRSS11E Lentivirus particle
    ORF Viral VectorpGMLPm002806mouse Tmprss11e Lentivirus plasmid
    ORF Viral VectorvGMLPm002806mouse Tmprss11e Lentivirus particle


    Target information

    Target IDGM-MP1849
    Target Name™PRSS11E
    Gene ID28983,305265,709278
    Gene Symbol and SynonymsDESC1,™PRSS11E,™PRSS11E2
    Uniprot AccessionQ9UL52
    Uniprot Entry Name™11E_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000087128
    Target ClassificationN/A

    The target: ™PRSS11E, gene name: ™PRSS11E, also named as DESC12, ™PRSS11E. Predicted to enable serine-type peptidase activity. Involved in cognition. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.