Anti-™PS5/ ™PRSS5/ SPINESIN monoclonal antibody

Anti-™PS5/ ™PRSS5/ SPINESIN antibody for FACS & in-vivo assay

Target products collectionGo to ™PRSS5/™PRSS5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1851-Ab-1/ GM-Tg-hg-MP1851-Ab-2Anti-Human ™PRSS5 monoclonal antibodyHuman
GM-Tg-rg-MP1851-Ab-1/ GM-Tg-rg-MP1851-Ab-2Anti-Rat ™PRSS5 monoclonal antibodyRat
GM-Tg-mg-MP1851-Ab-1/ GM-Tg-mg-MP1851-Ab-2Anti-Mouse ™PRSS5 monoclonal antibodyMouse
GM-Tg-cynog-MP1851-Ab-1/ GM-Tg-cynog-MP1851-Ab-2Anti-Cynomolgus/ Rhesus macaque ™PRSS5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1851-Ab-1/ GM-Tg-felg-MP1851-Ab-2Anti-Feline ™PRSS5 monoclonal antibodyFeline
GM-Tg-cang-MP1851-Ab-1/ GM-Tg-cang-MP1851-Ab-2Anti-Canine ™PRSS5 monoclonal antibodyCanine
GM-Tg-bovg-MP1851-Ab-1/ GM-Tg-bovg-MP1851-Ab-2Anti-Bovine ™PRSS5 monoclonal antibodyBovine
GM-Tg-equg-MP1851-Ab-1/ GM-Tg-equg-MP1851-Ab-2Anti-Equine ™PRSS5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1851-Ab-1/ GM-Tg-hg-MP1851-Ab-2; GM-Tg-rg-MP1851-Ab-1/ GM-Tg-rg-MP1851-Ab-2;
GM-Tg-mg-MP1851-Ab-1/ GM-Tg-mg-MP1851-Ab-2; GM-Tg-cynog-MP1851-Ab-1/ GM-Tg-cynog-MP1851-Ab-2;
GM-Tg-felg-MP1851-Ab-1/ GM-Tg-felg-MP1851-Ab-2; GM-Tg-cang-MP1851-Ab-1/ GM-Tg-cang-MP1851-Ab-2;
GM-Tg-bovg-MP1851-Ab-1/ GM-Tg-bovg-MP1851-Ab-2; GM-Tg-equg-MP1851-Ab-1/ GM-Tg-equg-MP1851-Ab-2
Products NameAnti-™PRSS5 monoclonal antibody
Formatmab
Target Name™PRSS5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™PRSS5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ™PS5/ ™PRSS5/ SPINESIN VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1851
    Target Name™PRSS5
    Gene ID80975,80893,266681,696419,611247,101082088,615090,100070705
    Gene Symbol and SynonymsAmp,SPINESIN,™PRSS5
    Uniprot AccessionQ9H3S3
    Uniprot Entry Name™PS5_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000166682
    Target ClassificationN/A

    The target: ™PRSS5, gene name: ™PRSS5, also named as SPINESIN. This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.