Anti-P5I13/ TP53I13/ DSCP1 monoclonal antibody

Anti-P5I13/ TP53I13/ DSCP1 antibody for FACS & in-vivo assay

Target products collectionGo to TP53I13/TP53I13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1860-Ab-1/ GM-Tg-hg-MP1860-Ab-2Anti-Human TP53I13 monoclonal antibodyHuman
GM-Tg-rg-MP1860-Ab-1/ GM-Tg-rg-MP1860-Ab-2Anti-Rat TP53I13 monoclonal antibodyRat
GM-Tg-mg-MP1860-Ab-1/ GM-Tg-mg-MP1860-Ab-2Anti-Mouse TP53I13 monoclonal antibodyMouse
GM-Tg-cynog-MP1860-Ab-1/ GM-Tg-cynog-MP1860-Ab-2Anti-Cynomolgus/ Rhesus macaque TP53I13 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1860-Ab-1/ GM-Tg-felg-MP1860-Ab-2Anti-Feline TP53I13 monoclonal antibodyFeline
GM-Tg-cang-MP1860-Ab-1/ GM-Tg-cang-MP1860-Ab-2Anti-Canine TP53I13 monoclonal antibodyCanine
GM-Tg-bovg-MP1860-Ab-1/ GM-Tg-bovg-MP1860-Ab-2Anti-Bovine TP53I13 monoclonal antibodyBovine
GM-Tg-equg-MP1860-Ab-1/ GM-Tg-equg-MP1860-Ab-2Anti-Equine TP53I13 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1860-Ab-1/ GM-Tg-hg-MP1860-Ab-2; GM-Tg-rg-MP1860-Ab-1/ GM-Tg-rg-MP1860-Ab-2;
GM-Tg-mg-MP1860-Ab-1/ GM-Tg-mg-MP1860-Ab-2; GM-Tg-cynog-MP1860-Ab-1/ GM-Tg-cynog-MP1860-Ab-2;
GM-Tg-felg-MP1860-Ab-1/ GM-Tg-felg-MP1860-Ab-2; GM-Tg-cang-MP1860-Ab-1/ GM-Tg-cang-MP1860-Ab-2;
GM-Tg-bovg-MP1860-Ab-1/ GM-Tg-bovg-MP1860-Ab-2; GM-Tg-equg-MP1860-Ab-1/ GM-Tg-equg-MP1860-Ab-2
Products NameAnti-TP53I13 monoclonal antibody
Formatmab
Target NameTP53I13
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TP53I13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species P5I13/ TP53I13/ DSCP1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1860
    Target NameTP53I13
    Gene ID90313,216964,287550,716918,611028,101092468,513556,100147229
    Gene Symbol and Synonyms2410019G02Rik,DSCP1,RGD1559818,TP53I13,Trp53i13
    Uniprot AccessionQ8NBR0,B0BN44
    Uniprot Entry NameP5I13_HUMAN,P5I13_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000167543
    Target ClassificationN/A

    The target: TP53I13, gene name: TP53I13, also named as DSCP1. Involved in several processes, including negative regulation of cell cycle; response to UV; and response to xenobiotic stimulus. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.