Anti-TSN33/ TSPAN33/ PEN monoclonal antibody

Anti-TSN33/ TSPAN33/ PEN antibody for FACS & in-vivo assay

Target products collectionGo to TSPAN33/TSPAN33 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1884-Ab-1/ GM-Tg-hg-MP1884-Ab-2Anti-Human TSPAN33 monoclonal antibodyHuman
GM-Tg-rg-MP1884-Ab-1/ GM-Tg-rg-MP1884-Ab-2Anti-Rat TSPAN33 monoclonal antibodyRat
GM-Tg-mg-MP1884-Ab-1/ GM-Tg-mg-MP1884-Ab-2Anti-Mouse TSPAN33 monoclonal antibodyMouse
GM-Tg-cynog-MP1884-Ab-1/ GM-Tg-cynog-MP1884-Ab-2Anti-Cynomolgus/ Rhesus macaque TSPAN33 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1884-Ab-1/ GM-Tg-felg-MP1884-Ab-2Anti-Feline TSPAN33 monoclonal antibodyFeline
GM-Tg-cang-MP1884-Ab-1/ GM-Tg-cang-MP1884-Ab-2Anti-Canine TSPAN33 monoclonal antibodyCanine
GM-Tg-bovg-MP1884-Ab-1/ GM-Tg-bovg-MP1884-Ab-2Anti-Bovine TSPAN33 monoclonal antibodyBovine
GM-Tg-equg-MP1884-Ab-1/ GM-Tg-equg-MP1884-Ab-2Anti-Equine TSPAN33 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1884-Ab-1/ GM-Tg-hg-MP1884-Ab-2; GM-Tg-rg-MP1884-Ab-1/ GM-Tg-rg-MP1884-Ab-2;
GM-Tg-mg-MP1884-Ab-1/ GM-Tg-mg-MP1884-Ab-2; GM-Tg-cynog-MP1884-Ab-1/ GM-Tg-cynog-MP1884-Ab-2;
GM-Tg-felg-MP1884-Ab-1/ GM-Tg-felg-MP1884-Ab-2; GM-Tg-cang-MP1884-Ab-1/ GM-Tg-cang-MP1884-Ab-2;
GM-Tg-bovg-MP1884-Ab-1/ GM-Tg-bovg-MP1884-Ab-2; GM-Tg-equg-MP1884-Ab-1/ GM-Tg-equg-MP1884-Ab-2
Products NameAnti-TSPAN33 monoclonal antibody
Formatmab
Target NameTSPAN33
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TSPAN33 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TSN33/ TSPAN33/ PEN VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP002594human TSPAN33 Lentivirus particle
    ORF Viral VectorpGMLP002594human TSPAN33 Lentivirus plasmid
    ORF Viral VectorpGMLPm001283mouse Tspan33 Lentivirus plasmid
    ORF Viral VectorvGMLPm001283mouse Tspan33 Lentivirus particle


    Target information

    Target IDGM-MP1884
    Target NameTSPAN33
    Gene ID340348,232670,500065,703028,475198,101083502,539284,100071801
    Gene Symbol and Synonyms1300010A20Rik,PEN,PEN.,RGD1560915,TSPAN-33,TSPAN33
    Uniprot AccessionQ86UF1,Q3SYV5
    Uniprot Entry NameTSN33_HUMAN,TSN33_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000158457
    Target ClassificationN/A

    The target: TSPAN33, gene name: TSPAN33, also named as PEN, PEN., TSPAN-33. Enables enzyme binding activity. Involved in pore complex assembly; protein localization to plasma membrane; and protein maturation. Located in plasma membrane. Part of pore complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.