Anti-TSN5/ TSPAN5/ NET-4 monoclonal antibody

Anti-TSN5/ TSPAN5/ NET-4 antibody for FACS & in-vivo assay

Target products collectionGo to TSPAN5/TSPAN5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1886-Ab-1/ GM-Tg-hg-MP1886-Ab-2Anti-Human TSPAN5 monoclonal antibodyHuman
GM-Tg-rg-MP1886-Ab-1/ GM-Tg-rg-MP1886-Ab-2Anti-Rat TSPAN5 monoclonal antibodyRat
GM-Tg-mg-MP1886-Ab-1/ GM-Tg-mg-MP1886-Ab-2Anti-Mouse TSPAN5 monoclonal antibodyMouse
GM-Tg-cynog-MP1886-Ab-1/ GM-Tg-cynog-MP1886-Ab-2Anti-Cynomolgus/ Rhesus macaque TSPAN5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1886-Ab-1/ GM-Tg-felg-MP1886-Ab-2Anti-Feline TSPAN5 monoclonal antibodyFeline
GM-Tg-cang-MP1886-Ab-1/ GM-Tg-cang-MP1886-Ab-2Anti-Canine TSPAN5 monoclonal antibodyCanine
GM-Tg-bovg-MP1886-Ab-1/ GM-Tg-bovg-MP1886-Ab-2Anti-Bovine TSPAN5 monoclonal antibodyBovine
GM-Tg-equg-MP1886-Ab-1/ GM-Tg-equg-MP1886-Ab-2Anti-Equine TSPAN5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1886-Ab-1/ GM-Tg-hg-MP1886-Ab-2; GM-Tg-rg-MP1886-Ab-1/ GM-Tg-rg-MP1886-Ab-2;
GM-Tg-mg-MP1886-Ab-1/ GM-Tg-mg-MP1886-Ab-2; GM-Tg-cynog-MP1886-Ab-1/ GM-Tg-cynog-MP1886-Ab-2;
GM-Tg-felg-MP1886-Ab-1/ GM-Tg-felg-MP1886-Ab-2; GM-Tg-cang-MP1886-Ab-1/ GM-Tg-cang-MP1886-Ab-2;
GM-Tg-bovg-MP1886-Ab-1/ GM-Tg-bovg-MP1886-Ab-2; GM-Tg-equg-MP1886-Ab-1/ GM-Tg-equg-MP1886-Ab-2
Products NameAnti-TSPAN5 monoclonal antibody
Formatmab
Target NameTSPAN5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TSPAN5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TSN5/ TSPAN5/ NET-4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1886
    Target NameTSPAN5
    Gene ID10098,56224,362048,706537,478486,101088926,538668,100053658
    Gene Symbol and Synonyms2810455A09Rik,4930505M03Rik,NET-4,NET4,™4SF9,TSPAN-5,TSPAN5
    Uniprot AccessionP62079,Q68VK5,Q17QJ5
    Uniprot Entry NameTSN5_HUMAN,TSN5_RAT,TSN5_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168785
    Target ClassificationN/A

    The target: TSPAN5, gene name: TSPAN5, also named as NET-4, NET4, ™4SF9, TSPAN-5. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.