Anti-UNC5D/ PRO34692/ Unc5h4 monoclonal antibody

Anti-UNC5D/ PRO34692/ Unc5h4 antibody for FACS & in-vivo assay

Target products collectionGo to UNC5D/UNC5D products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1904-Ab-1/ GM-Tg-hg-MP1904-Ab-2Anti-Human UNC5D monoclonal antibodyHuman
GM-Tg-rg-MP1904-Ab-1/ GM-Tg-rg-MP1904-Ab-2Anti-Rat UNC5D monoclonal antibodyRat
GM-Tg-mg-MP1904-Ab-1/ GM-Tg-mg-MP1904-Ab-2Anti-Mouse UNC5D monoclonal antibodyMouse
GM-Tg-cynog-MP1904-Ab-1/ GM-Tg-cynog-MP1904-Ab-2Anti-Cynomolgus/ Rhesus macaque UNC5D monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1904-Ab-1/ GM-Tg-felg-MP1904-Ab-2Anti-Feline UNC5D monoclonal antibodyFeline
GM-Tg-cang-MP1904-Ab-1/ GM-Tg-cang-MP1904-Ab-2Anti-Canine UNC5D monoclonal antibodyCanine
GM-Tg-bovg-MP1904-Ab-1/ GM-Tg-bovg-MP1904-Ab-2Anti-Bovine UNC5D monoclonal antibodyBovine
GM-Tg-equg-MP1904-Ab-1/ GM-Tg-equg-MP1904-Ab-2Anti-Equine UNC5D monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1904-Ab-1/ GM-Tg-hg-MP1904-Ab-2; GM-Tg-rg-MP1904-Ab-1/ GM-Tg-rg-MP1904-Ab-2;
GM-Tg-mg-MP1904-Ab-1/ GM-Tg-mg-MP1904-Ab-2; GM-Tg-cynog-MP1904-Ab-1/ GM-Tg-cynog-MP1904-Ab-2;
GM-Tg-felg-MP1904-Ab-1/ GM-Tg-felg-MP1904-Ab-2; GM-Tg-cang-MP1904-Ab-1/ GM-Tg-cang-MP1904-Ab-2;
GM-Tg-bovg-MP1904-Ab-1/ GM-Tg-bovg-MP1904-Ab-2; GM-Tg-equg-MP1904-Ab-1/ GM-Tg-equg-MP1904-Ab-2
Products NameAnti-UNC5D monoclonal antibody
Formatmab
Target NameUNC5D
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-UNC5D benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species UNC5D/ PRO34692/ Unc5h4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1904
    Target NameUNC5D
    Gene ID137970,210801,306534,697619,482857,101101462,520004,100058060
    Gene Symbol and SynonymsD930029E11Rik,mKIAA1777,PRO34692,UNC5D,Unc5h4
    Uniprot AccessionQ6UXZ4,F1LW30
    Uniprot Entry NameUNC5D_HUMAN,UNC5D_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000156687
    Target ClassificationN/A

    The target: UNC5D, gene name: UNC5D, also named as PRO34692, Unc5h4. Predicted to enable netrin receptor activity. Involved in cell-cell adhesion via plasma-membrane adhesion molecules. Predicted to be located in cell surface and plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.