Anti-VAPA/ VAP-33/ VAP-A monoclonal antibody

Anti-VAPA/ VAP-33/ VAP-A antibody for FACS & in-vivo assay

Target products collectionGo to VAPA/VAPA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1917-Ab-1/ GM-Tg-hg-MP1917-Ab-2Anti-Human VAPA monoclonal antibodyHuman
GM-Tg-rg-MP1917-Ab-1/ GM-Tg-rg-MP1917-Ab-2Anti-Rat VAPA monoclonal antibodyRat
GM-Tg-mg-MP1917-Ab-1/ GM-Tg-mg-MP1917-Ab-2Anti-Mouse VAPA monoclonal antibodyMouse
GM-Tg-cynog-MP1917-Ab-1/ GM-Tg-cynog-MP1917-Ab-2Anti-Cynomolgus/ Rhesus macaque VAPA monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1917-Ab-1/ GM-Tg-felg-MP1917-Ab-2Anti-Feline VAPA monoclonal antibodyFeline
GM-Tg-cang-MP1917-Ab-1/ GM-Tg-cang-MP1917-Ab-2Anti-Canine VAPA monoclonal antibodyCanine
GM-Tg-bovg-MP1917-Ab-1/ GM-Tg-bovg-MP1917-Ab-2Anti-Bovine VAPA monoclonal antibodyBovine
GM-Tg-equg-MP1917-Ab-1/ GM-Tg-equg-MP1917-Ab-2Anti-Equine VAPA monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1917-Ab-1/ GM-Tg-hg-MP1917-Ab-2; GM-Tg-rg-MP1917-Ab-1/ GM-Tg-rg-MP1917-Ab-2;
GM-Tg-mg-MP1917-Ab-1/ GM-Tg-mg-MP1917-Ab-2; GM-Tg-cynog-MP1917-Ab-1/ GM-Tg-cynog-MP1917-Ab-2;
GM-Tg-felg-MP1917-Ab-1/ GM-Tg-felg-MP1917-Ab-2; GM-Tg-cang-MP1917-Ab-1/ GM-Tg-cang-MP1917-Ab-2;
GM-Tg-bovg-MP1917-Ab-1/ GM-Tg-bovg-MP1917-Ab-2; GM-Tg-equg-MP1917-Ab-1/ GM-Tg-equg-MP1917-Ab-2
Products NameAnti-VAPA monoclonal antibody
Formatmab
Target NameVAPA
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VAPA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species VAPA/ VAP-33/ VAP-A VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1917
    Target NameVAPA
    Gene ID9218,30960,58857,114669839,480208,101100344,516024,100055344
    Gene Symbol and Synonyms33kDa,hVAP-33,VAMP-A,VAP-33,VAP-A,VAP33,VAPA
    Uniprot AccessionQ9P0L0,Q9Z270,Q0VCY1
    Uniprot Entry NameVAPA_HUMAN,VAPA_RAT,VAPA_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000101558
    Target ClassificationN/A

    The target: VAPA, gene name: VAPA, also named as VAP-33, VAP-A, VAP33, hVAP-33. The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.