Anti-VASN/ SLITL2 monoclonal antibody

Anti-VASN/ SLITL2 antibody for FACS & in-vivo assay

Target products collectionGo to VASN/VASN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1919-Ab-1/ GM-Tg-hg-MP1919-Ab-2Anti-Human VASN monoclonal antibodyHuman
GM-Tg-rg-MP1919-Ab-1/ GM-Tg-rg-MP1919-Ab-2Anti-Rat VASN monoclonal antibodyRat
GM-Tg-mg-MP1919-Ab-1/ GM-Tg-mg-MP1919-Ab-2Anti-Mouse VASN monoclonal antibodyMouse
GM-Tg-cynog-MP1919-Ab-1/ GM-Tg-cynog-MP1919-Ab-2Anti-Cynomolgus/ Rhesus macaque VASN monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1919-Ab-1/ GM-Tg-felg-MP1919-Ab-2Anti-Feline VASN monoclonal antibodyFeline
GM-Tg-cang-MP1919-Ab-1/ GM-Tg-cang-MP1919-Ab-2Anti-Canine VASN monoclonal antibodyCanine
GM-Tg-bovg-MP1919-Ab-1/ GM-Tg-bovg-MP1919-Ab-2Anti-Bovine VASN monoclonal antibodyBovine
GM-Tg-equg-MP1919-Ab-1/ GM-Tg-equg-MP1919-Ab-2Anti-Equine VASN monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1919-Ab-1/ GM-Tg-hg-MP1919-Ab-2; GM-Tg-rg-MP1919-Ab-1/ GM-Tg-rg-MP1919-Ab-2;
GM-Tg-mg-MP1919-Ab-1/ GM-Tg-mg-MP1919-Ab-2; GM-Tg-cynog-MP1919-Ab-1/ GM-Tg-cynog-MP1919-Ab-2;
GM-Tg-felg-MP1919-Ab-1/ GM-Tg-felg-MP1919-Ab-2; GM-Tg-cang-MP1919-Ab-1/ GM-Tg-cang-MP1919-Ab-2;
GM-Tg-bovg-MP1919-Ab-1/ GM-Tg-bovg-MP1919-Ab-2; GM-Tg-equg-MP1919-Ab-1/ GM-Tg-equg-MP1919-Ab-2
Products NameAnti-VASN monoclonal antibody
Formatmab
Target NameVASN
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VASN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species VASN/ SLITL2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1919
    Target NameVASN
    Gene ID114990,246154,679921,100426861,100688709,101094722,787995,100629909
    Gene Symbol and Synonyms2610528G05Rik,Atia,SLITL2,VASN
    Uniprot AccessionQ6EMK4
    Uniprot Entry NameVASN_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168140
    Target ClassificationN/A

    The target: VASN, gene name: VASN, also named as SLITL2. Enables transforming growth factor beta binding activity. Involved in negative regulation of epithelial to mesenchymal transition and negative regulation of transforming growth factor beta receptor signaling pathway. Located in cell surface and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.