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Anti-VSIG1/ 1700062D20Rik/ GPA34 monoclonal antibody
Anti-VSIG1/ 1700062D20Rik/ GPA34 antibody for FACS & in-vivo assay
Go to VSIG1/VSIG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1929-Ab-1/ GM-Tg-hg-MP1929-Ab-2 | Anti-Human VSIG1 monoclonal antibody | Human |
| GM-Tg-rg-MP1929-Ab-1/ GM-Tg-rg-MP1929-Ab-2 | Anti-Rat VSIG1 monoclonal antibody | Rat |
| GM-Tg-mg-MP1929-Ab-1/ GM-Tg-mg-MP1929-Ab-2 | Anti-Mouse VSIG1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1929-Ab-1/ GM-Tg-cynog-MP1929-Ab-2 | Anti-Cynomolgus/ Rhesus macaque VSIG1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1929-Ab-1/ GM-Tg-felg-MP1929-Ab-2 | Anti-Feline VSIG1 monoclonal antibody | Feline |
| GM-Tg-cang-MP1929-Ab-1/ GM-Tg-cang-MP1929-Ab-2 | Anti-Canine VSIG1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1929-Ab-1/ GM-Tg-bovg-MP1929-Ab-2 | Anti-Bovine VSIG1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1929-Ab-1/ GM-Tg-equg-MP1929-Ab-2 | Anti-Equine VSIG1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1929-Ab-1/ GM-Tg-hg-MP1929-Ab-2; GM-Tg-rg-MP1929-Ab-1/ GM-Tg-rg-MP1929-Ab-2; GM-Tg-mg-MP1929-Ab-1/ GM-Tg-mg-MP1929-Ab-2; GM-Tg-cynog-MP1929-Ab-1/ GM-Tg-cynog-MP1929-Ab-2; GM-Tg-felg-MP1929-Ab-1/ GM-Tg-felg-MP1929-Ab-2; GM-Tg-cang-MP1929-Ab-1/ GM-Tg-cang-MP1929-Ab-2; GM-Tg-bovg-MP1929-Ab-1/ GM-Tg-bovg-MP1929-Ab-2; GM-Tg-equg-MP1929-Ab-1/ GM-Tg-equg-MP1929-Ab-2 |
| Products Name | Anti-VSIG1 monoclonal antibody |
| Format | mab |
| Target Name | VSIG1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-VSIG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species VSIG1/ 1700062D20Rik/ GPA34 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1929 |
| Target Name | VSIG1 |
| Gene ID | 340547,78789,315920,703739,481013,101089246,505937,100060202 |
| Gene Symbol and Synonyms | 1700062D20Rik,4930405J24Rik,dJ889N15.1,GPA34,VSIG1 |
| Uniprot Accession | Q86XK7,Q4KLY3,Q29RR6 |
| Uniprot Entry Name | VSIG1_HUMAN,VSIG1_RAT,VSIG1_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000101842 |
| Target Classification | N/A |
The target: VSIG1, gene name: VSIG1, also named as 1700062D20Rik, GPA34, dJ889N15.1. This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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