Anti-XKR5/ HARL2754/ UNQ2754 monoclonal antibody

Anti-XKR5/ HARL2754/ UNQ2754 antibody for FACS & in-vivo assay

Target products collectionGo to XKR5/XKR5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1944-Ab-1/ GM-Tg-hg-MP1944-Ab-2Anti-Human XKR5 monoclonal antibodyHuman
GM-Tg-rg-MP1944-Ab-1/ GM-Tg-rg-MP1944-Ab-2Anti-Rat XKR5 monoclonal antibodyRat
GM-Tg-mg-MP1944-Ab-1/ GM-Tg-mg-MP1944-Ab-2Anti-Mouse XKR5 monoclonal antibodyMouse
GM-Tg-cynog-MP1944-Ab-1/ GM-Tg-cynog-MP1944-Ab-2Anti-Cynomolgus/ Rhesus macaque XKR5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1944-Ab-1/ GM-Tg-felg-MP1944-Ab-2Anti-Feline XKR5 monoclonal antibodyFeline
GM-Tg-cang-MP1944-Ab-1/ GM-Tg-cang-MP1944-Ab-2Anti-Canine XKR5 monoclonal antibodyCanine
GM-Tg-bovg-MP1944-Ab-1/ GM-Tg-bovg-MP1944-Ab-2Anti-Bovine XKR5 monoclonal antibodyBovine
GM-Tg-equg-MP1944-Ab-1/ GM-Tg-equg-MP1944-Ab-2Anti-Equine XKR5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1944-Ab-1/ GM-Tg-hg-MP1944-Ab-2; GM-Tg-rg-MP1944-Ab-1/ GM-Tg-rg-MP1944-Ab-2;
GM-Tg-mg-MP1944-Ab-1/ GM-Tg-mg-MP1944-Ab-2; GM-Tg-cynog-MP1944-Ab-1/ GM-Tg-cynog-MP1944-Ab-2;
GM-Tg-felg-MP1944-Ab-1/ GM-Tg-felg-MP1944-Ab-2; GM-Tg-cang-MP1944-Ab-1/ GM-Tg-cang-MP1944-Ab-2;
GM-Tg-bovg-MP1944-Ab-1/ GM-Tg-bovg-MP1944-Ab-2; GM-Tg-equg-MP1944-Ab-1/ GM-Tg-equg-MP1944-Ab-2
Products NameAnti-XKR5 monoclonal antibody
Formatmab
Target NameXKR5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-XKR5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species XKR5/ HARL2754/ UNQ2754 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1944
    Target NameXKR5
    Gene ID389610,319581,497083,716883,482942,101083075,529365,100063897
    Gene Symbol and Synonyms5430438H03Rik,HARL2754,UNQ2754,XKR5,XRG5,XRG5A,XRG5BM
    Uniprot AccessionQ6UX68
    Uniprot Entry NameXKR5_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000275591
    Target ClassificationN/A

    The target: XKR5, gene name: XKR5, also named as HARL2754, UNQ2754, XRG5A, XRG5BM. Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.