Anti-XKR2/ XKRX/ XPLAC monoclonal antibody

Anti-XKR2/ XKRX/ XPLAC antibody for FACS & in-vivo assay

Target products collectionGo to XKRX/XKRX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1949-Ab-1/ GM-Tg-hg-MP1949-Ab-2Anti-Human XKRX monoclonal antibodyHuman
GM-Tg-rg-MP1949-Ab-1/ GM-Tg-rg-MP1949-Ab-2Anti-Rat XKRX monoclonal antibodyRat
GM-Tg-mg-MP1949-Ab-1/ GM-Tg-mg-MP1949-Ab-2Anti-Mouse XKRX monoclonal antibodyMouse
GM-Tg-cynog-MP1949-Ab-1/ GM-Tg-cynog-MP1949-Ab-2Anti-Cynomolgus/ Rhesus macaque XKRX monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1949-Ab-1/ GM-Tg-felg-MP1949-Ab-2Anti-Feline XKRX monoclonal antibodyFeline
GM-Tg-cang-MP1949-Ab-1/ GM-Tg-cang-MP1949-Ab-2Anti-Canine XKRX monoclonal antibodyCanine
GM-Tg-bovg-MP1949-Ab-1/ GM-Tg-bovg-MP1949-Ab-2Anti-Bovine XKRX monoclonal antibodyBovine
GM-Tg-equg-MP1949-Ab-1/ GM-Tg-equg-MP1949-Ab-2Anti-Equine XKRX monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1949-Ab-1/ GM-Tg-hg-MP1949-Ab-2; GM-Tg-rg-MP1949-Ab-1/ GM-Tg-rg-MP1949-Ab-2;
GM-Tg-mg-MP1949-Ab-1/ GM-Tg-mg-MP1949-Ab-2; GM-Tg-cynog-MP1949-Ab-1/ GM-Tg-cynog-MP1949-Ab-2;
GM-Tg-felg-MP1949-Ab-1/ GM-Tg-felg-MP1949-Ab-2; GM-Tg-cang-MP1949-Ab-1/ GM-Tg-cang-MP1949-Ab-2;
GM-Tg-bovg-MP1949-Ab-1/ GM-Tg-bovg-MP1949-Ab-2; GM-Tg-equg-MP1949-Ab-1/ GM-Tg-equg-MP1949-Ab-2
Products NameAnti-XKRX monoclonal antibody
Formatmab
Target NameXKRX
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-XKRX benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species XKR2/ XKRX/ XPLAC VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1949
    Target NameXKRX
    Gene ID402415,331524,497101,701721,119868472,101090924,524975,100060004
    Gene Symbol and SynonymsA630026F04,XKR2,XKRX,XPLAC,XRG2
    Uniprot AccessionQ6PP77,Q5GH60
    Uniprot Entry NameXKR2_HUMAN,XKR2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000182489
    Target ClassificationN/A

    The target: XKRX, gene name: XKRX, also named as XKR2, XPLAC, XRG2. This gene encodes a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.