Anti-ZAN monoclonal antibody

Anti-ZAN antibody for FACS & in-vivo assay

Target products collectionGo to ZAN/ZAN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1956-Ab-1/ GM-Tg-hg-MP1956-Ab-2Anti-Human ZAN monoclonal antibodyHuman
GM-Tg-rg-MP1956-Ab-1/ GM-Tg-rg-MP1956-Ab-2Anti-Rat ZAN monoclonal antibodyRat
GM-Tg-mg-MP1956-Ab-1/ GM-Tg-mg-MP1956-Ab-2Anti-Mouse ZAN monoclonal antibodyMouse
GM-Tg-cynog-MP1956-Ab-1/ GM-Tg-cynog-MP1956-Ab-2Anti-Cynomolgus/ Rhesus macaque ZAN monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1956-Ab-1/ GM-Tg-felg-MP1956-Ab-2Anti-Feline ZAN monoclonal antibodyFeline
GM-Tg-cang-MP1956-Ab-1/ GM-Tg-cang-MP1956-Ab-2Anti-Canine ZAN monoclonal antibodyCanine
GM-Tg-bovg-MP1956-Ab-1/ GM-Tg-bovg-MP1956-Ab-2Anti-Bovine ZAN monoclonal antibodyBovine
GM-Tg-equg-MP1956-Ab-1/ GM-Tg-equg-MP1956-Ab-2Anti-Equine ZAN monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1956-Ab-1/ GM-Tg-hg-MP1956-Ab-2; GM-Tg-rg-MP1956-Ab-1/ GM-Tg-rg-MP1956-Ab-2;
GM-Tg-mg-MP1956-Ab-1/ GM-Tg-mg-MP1956-Ab-2; GM-Tg-cynog-MP1956-Ab-1/ GM-Tg-cynog-MP1956-Ab-2;
GM-Tg-felg-MP1956-Ab-1/ GM-Tg-felg-MP1956-Ab-2; GM-Tg-cang-MP1956-Ab-1/ GM-Tg-cang-MP1956-Ab-2;
GM-Tg-bovg-MP1956-Ab-1/ GM-Tg-bovg-MP1956-Ab-2; GM-Tg-equg-MP1956-Ab-1/ GM-Tg-equg-MP1956-Ab-2
Products NameAnti-ZAN monoclonal antibody
Formatmab
Target NameZAN
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ZAN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ZAN VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1956
    Target NameZAN
    Gene ID7455,22635,304379,613228,102156947,102902284,530271,100147025
    Gene Symbol and SynonymsZAN,Zan-test
    Uniprot AccessionQ9Y493
    Uniprot Entry NameZAN_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000146839
    Target ClassificationN/A

    The target: ZAN, gene name: ZAN, also named as . This gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. The encoded protein is located in the acrosome and may be involved in signaling or gamete recognition. An allelic polymorphism in this gene results in both functional and frameshifted alleles; the reference genome represents the functional allele. Alternative splicing of this gene results in multiple transcript variants..



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.