Anti-ZDH22/ ZDHHC22/ C14orf59 monoclonal antibody

Anti-ZDH22/ ZDHHC22/ C14orf59 antibody for FACS & in-vivo assay

Target products collectionGo to ZDHHC22/ZDHHC22 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1960-Ab-1/ GM-Tg-hg-MP1960-Ab-2Anti-Human ZDHHC22 monoclonal antibodyHuman
GM-Tg-rg-MP1960-Ab-1/ GM-Tg-rg-MP1960-Ab-2Anti-Rat ZDHHC22 monoclonal antibodyRat
GM-Tg-mg-MP1960-Ab-1/ GM-Tg-mg-MP1960-Ab-2Anti-Mouse ZDHHC22 monoclonal antibodyMouse
GM-Tg-cynog-MP1960-Ab-1/ GM-Tg-cynog-MP1960-Ab-2Anti-Cynomolgus/ Rhesus macaque ZDHHC22 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1960-Ab-1/ GM-Tg-felg-MP1960-Ab-2Anti-Feline ZDHHC22 monoclonal antibodyFeline
GM-Tg-cang-MP1960-Ab-1/ GM-Tg-cang-MP1960-Ab-2Anti-Canine ZDHHC22 monoclonal antibodyCanine
GM-Tg-bovg-MP1960-Ab-1/ GM-Tg-bovg-MP1960-Ab-2Anti-Bovine ZDHHC22 monoclonal antibodyBovine
GM-Tg-equg-MP1960-Ab-1/ GM-Tg-equg-MP1960-Ab-2Anti-Equine ZDHHC22 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1960-Ab-1/ GM-Tg-hg-MP1960-Ab-2; GM-Tg-rg-MP1960-Ab-1/ GM-Tg-rg-MP1960-Ab-2;
GM-Tg-mg-MP1960-Ab-1/ GM-Tg-mg-MP1960-Ab-2; GM-Tg-cynog-MP1960-Ab-1/ GM-Tg-cynog-MP1960-Ab-2;
GM-Tg-felg-MP1960-Ab-1/ GM-Tg-felg-MP1960-Ab-2; GM-Tg-cang-MP1960-Ab-1/ GM-Tg-cang-MP1960-Ab-2;
GM-Tg-bovg-MP1960-Ab-1/ GM-Tg-bovg-MP1960-Ab-2; GM-Tg-equg-MP1960-Ab-1/ GM-Tg-equg-MP1960-Ab-2
Products NameAnti-ZDHHC22 monoclonal antibody
Formatmab
Target NameZDHHC22
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ZDHHC22 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ZDH22/ ZDHHC22/ C14orf59 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1960
    Target NameZDHHC22
    Gene ID283576,238331,299211,706468,100686021,101100646,613943,100058967
    Gene Symbol and SynonymsC14orf59,Gm262,ZDHHC22
    Uniprot AccessionQ8N966,Q2TGI8
    Uniprot Entry NameZDH22_HUMAN,ZDH22_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000177108
    Target ClassificationN/A

    The target: ZDHHC22, gene name: ZDHHC22, also named as C14orf59. Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in protein localization to plasma membrane and protein palmitoylation. Located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.