Anti-ZDHC5/ ZDHHC5/ DHHC5 monoclonal antibody

Anti-ZDHC5/ ZDHHC5/ DHHC5 antibody for FACS & in-vivo assay

Target products collectionGo to ZDHHC5/ZDHHC5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1962-Ab-1/ GM-Tg-hg-MP1962-Ab-2Anti-Human ZDHHC5 monoclonal antibodyHuman
GM-Tg-rg-MP1962-Ab-1/ GM-Tg-rg-MP1962-Ab-2Anti-Rat ZDHHC5 monoclonal antibodyRat
GM-Tg-mg-MP1962-Ab-1/ GM-Tg-mg-MP1962-Ab-2Anti-Mouse ZDHHC5 monoclonal antibodyMouse
GM-Tg-cynog-MP1962-Ab-1/ GM-Tg-cynog-MP1962-Ab-2Anti-Cynomolgus/ Rhesus macaque ZDHHC5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1962-Ab-1/ GM-Tg-felg-MP1962-Ab-2Anti-Feline ZDHHC5 monoclonal antibodyFeline
GM-Tg-cang-MP1962-Ab-1/ GM-Tg-cang-MP1962-Ab-2Anti-Canine ZDHHC5 monoclonal antibodyCanine
GM-Tg-bovg-MP1962-Ab-1/ GM-Tg-bovg-MP1962-Ab-2Anti-Bovine ZDHHC5 monoclonal antibodyBovine
GM-Tg-equg-MP1962-Ab-1/ GM-Tg-equg-MP1962-Ab-2Anti-Equine ZDHHC5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1962-Ab-1/ GM-Tg-hg-MP1962-Ab-2; GM-Tg-rg-MP1962-Ab-1/ GM-Tg-rg-MP1962-Ab-2;
GM-Tg-mg-MP1962-Ab-1/ GM-Tg-mg-MP1962-Ab-2; GM-Tg-cynog-MP1962-Ab-1/ GM-Tg-cynog-MP1962-Ab-2;
GM-Tg-felg-MP1962-Ab-1/ GM-Tg-felg-MP1962-Ab-2; GM-Tg-cang-MP1962-Ab-1/ GM-Tg-cang-MP1962-Ab-2;
GM-Tg-bovg-MP1962-Ab-1/ GM-Tg-bovg-MP1962-Ab-2; GM-Tg-equg-MP1962-Ab-1/ GM-Tg-equg-MP1962-Ab-2
Products NameAnti-ZDHHC5 monoclonal antibody
Formatmab
Target NameZDHHC5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ZDHHC5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ZDHC5/ ZDHHC5/ DHHC5 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1962
    Target NameZDHHC5
    Gene ID25921,228136,362156,704863,483490,101091476,533250,100066506
    Gene Symbol and Synonyms1110032A17Rik,DHHC-5,DHHC5,ZDHHC5,Zisp,ZNF375
    Uniprot AccessionQ9C0B5,Q2THW7,Q2THW9,E1BLT8
    Uniprot Entry NameZDHC5_HUMAN,ZDHC5_RAT,ZDHC5_CANLF,ZDHC5_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000156599
    Target ClassificationN/A

    The target: ZDHHC5, gene name: ZDHHC5, also named as DHHC5, ZNF375. Enables palmitoyltransferase activity. Involved in positive regulation of pattern recognition receptor signaling pathway and positive regulation of protein localization to plasma membrane. Acts upstream of or within protein palmitoylation. Located in phagocytic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.