Anti-ADAP1/ CENTA1/ GCS1L monoclonal antibody

Anti-ADAP1/ CENTA1/ GCS1L antibody for FACS & in-vivo assay

Target products collectionGo to ADAP1/ADAP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1968-Ab-1/ GM-Tg-hg-MP1968-Ab-2Anti-Human ADAP1 monoclonal antibodyHuman
GM-Tg-rg-MP1968-Ab-1/ GM-Tg-rg-MP1968-Ab-2Anti-Rat ADAP1 monoclonal antibodyRat
GM-Tg-mg-MP1968-Ab-1/ GM-Tg-mg-MP1968-Ab-2Anti-Mouse ADAP1 monoclonal antibodyMouse
GM-Tg-cynog-MP1968-Ab-1/ GM-Tg-cynog-MP1968-Ab-2Anti-Cynomolgus/ Rhesus macaque ADAP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1968-Ab-1/ GM-Tg-felg-MP1968-Ab-2Anti-Feline ADAP1 monoclonal antibodyFeline
GM-Tg-cang-MP1968-Ab-1/ GM-Tg-cang-MP1968-Ab-2Anti-Canine ADAP1 monoclonal antibodyCanine
GM-Tg-bovg-MP1968-Ab-1/ GM-Tg-bovg-MP1968-Ab-2Anti-Bovine ADAP1 monoclonal antibodyBovine
GM-Tg-equg-MP1968-Ab-1/ GM-Tg-equg-MP1968-Ab-2Anti-Equine ADAP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1968-Ab-1/ GM-Tg-hg-MP1968-Ab-2; GM-Tg-rg-MP1968-Ab-1/ GM-Tg-rg-MP1968-Ab-2;
GM-Tg-mg-MP1968-Ab-1/ GM-Tg-mg-MP1968-Ab-2; GM-Tg-cynog-MP1968-Ab-1/ GM-Tg-cynog-MP1968-Ab-2;
GM-Tg-felg-MP1968-Ab-1/ GM-Tg-felg-MP1968-Ab-2; GM-Tg-cang-MP1968-Ab-1/ GM-Tg-cang-MP1968-Ab-2;
GM-Tg-bovg-MP1968-Ab-1/ GM-Tg-bovg-MP1968-Ab-2; GM-Tg-equg-MP1968-Ab-1/ GM-Tg-equg-MP1968-Ab-2
Products NameAnti-ADAP1 monoclonal antibody
Formatmab
Target NameADAP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ADAP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ADAP1/ CENTA1/ GCS1L VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1968
    Target NameADAP1
    Gene ID11033,231821,171097,696246,606942,101088290,282176,100630912
    Gene Symbol and Synonyms4930431P11Rik,ADAP1,CENTA1,GC1L,GCS1L,p42IP4
    Uniprot AccessionO75689
    Uniprot Entry NameADAP1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000105963
    Target ClassificationN/A

    The target: ADAP1, gene name: ADAP1, also named as CENTA1, GCS1L, p42IP4. Enables GTPase activator activity. Involved in regulation of GTPase activity. Located in cytosol; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.