Anti-ADDA/ ADD1 monoclonal antibody

Anti-ADDA/ ADD1 antibody for FACS & in-vivo assay

Target products collectionGo to ADD1/ADD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1969-Ab-1/ GM-Tg-hg-MP1969-Ab-2Anti-Human ADD1 monoclonal antibodyHuman
GM-Tg-rg-MP1969-Ab-1/ GM-Tg-rg-MP1969-Ab-2Anti-Rat ADD1 monoclonal antibodyRat
GM-Tg-mg-MP1969-Ab-1/ GM-Tg-mg-MP1969-Ab-2Anti-Mouse ADD1 monoclonal antibodyMouse
GM-Tg-cynog-MP1969-Ab-1/ GM-Tg-cynog-MP1969-Ab-2Anti-Cynomolgus/ Rhesus macaque ADD1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1969-Ab-1/ GM-Tg-felg-MP1969-Ab-2Anti-Feline ADD1 monoclonal antibodyFeline
GM-Tg-cang-MP1969-Ab-1/ GM-Tg-cang-MP1969-Ab-2Anti-Canine ADD1 monoclonal antibodyCanine
GM-Tg-bovg-MP1969-Ab-1/ GM-Tg-bovg-MP1969-Ab-2Anti-Bovine ADD1 monoclonal antibodyBovine
GM-Tg-equg-MP1969-Ab-1/ GM-Tg-equg-MP1969-Ab-2Anti-Equine ADD1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1969-Ab-1/ GM-Tg-hg-MP1969-Ab-2; GM-Tg-rg-MP1969-Ab-1/ GM-Tg-rg-MP1969-Ab-2;
GM-Tg-mg-MP1969-Ab-1/ GM-Tg-mg-MP1969-Ab-2; GM-Tg-cynog-MP1969-Ab-1/ GM-Tg-cynog-MP1969-Ab-2;
GM-Tg-felg-MP1969-Ab-1/ GM-Tg-felg-MP1969-Ab-2; GM-Tg-cang-MP1969-Ab-1/ GM-Tg-cang-MP1969-Ab-2;
GM-Tg-bovg-MP1969-Ab-1/ GM-Tg-bovg-MP1969-Ab-2; GM-Tg-equg-MP1969-Ab-1/ GM-Tg-equg-MP1969-Ab-2
Products NameAnti-ADD1 monoclonal antibody
Formatmab
Target NameADD1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ADD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ADDA/ ADD1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1969
    Target NameADD1
    Gene ID118,11518,24170,700805,488796,101097481,507193,100051451
    Gene Symbol and SynonymsADD1,ADDA
    Uniprot AccessionP35611,Q63028
    Uniprot Entry NameADDA_HUMAN,ADDA_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000087274
    Target ClassificationN/A

    The target: ADD1, gene name: ADD1, also named as ADDA. Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.