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Anti-ADRM1/ ARM-1/ ARM1 monoclonal antibody
Anti-ADRM1/ ARM-1/ ARM1 antibody for FACS & in-vivo assay
Go to ADRM1/ADRM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1975-Ab-1/ GM-Tg-hg-MP1975-Ab-2 | Anti-Human ADRM1 monoclonal antibody | Human |
| GM-Tg-rg-MP1975-Ab-1/ GM-Tg-rg-MP1975-Ab-2 | Anti-Rat ADRM1 monoclonal antibody | Rat |
| GM-Tg-mg-MP1975-Ab-1/ GM-Tg-mg-MP1975-Ab-2 | Anti-Mouse ADRM1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1975-Ab-1/ GM-Tg-cynog-MP1975-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ADRM1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1975-Ab-1/ GM-Tg-felg-MP1975-Ab-2 | Anti-Feline ADRM1 monoclonal antibody | Feline |
| GM-Tg-cang-MP1975-Ab-1/ GM-Tg-cang-MP1975-Ab-2 | Anti-Canine ADRM1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1975-Ab-1/ GM-Tg-bovg-MP1975-Ab-2 | Anti-Bovine ADRM1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1975-Ab-1/ GM-Tg-equg-MP1975-Ab-2 | Anti-Equine ADRM1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1975-Ab-1/ GM-Tg-hg-MP1975-Ab-2; GM-Tg-rg-MP1975-Ab-1/ GM-Tg-rg-MP1975-Ab-2; GM-Tg-mg-MP1975-Ab-1/ GM-Tg-mg-MP1975-Ab-2; GM-Tg-cynog-MP1975-Ab-1/ GM-Tg-cynog-MP1975-Ab-2; GM-Tg-felg-MP1975-Ab-1/ GM-Tg-felg-MP1975-Ab-2; GM-Tg-cang-MP1975-Ab-1/ GM-Tg-cang-MP1975-Ab-2; GM-Tg-bovg-MP1975-Ab-1/ GM-Tg-bovg-MP1975-Ab-2; GM-Tg-equg-MP1975-Ab-1/ GM-Tg-equg-MP1975-Ab-2 |
| Products Name | Anti-ADRM1 monoclonal antibody |
| Format | mab |
| Target Name | ADRM1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ADRM1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ADRM1/ ARM-1/ ARM1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003926 | human ADRM1 Lentivirus particle |
| ORF Viral Vector | pGMLP003926 | human ADRM1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002328 | mouse Adrm1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002328 | mouse Adrm1 Lentivirus particle |
Target information
| Target ID | GM-MP1975 |
| Target Name | ADRM1 |
| Gene ID | 11047,56436,65138,699928,100855986,101097227,519729,100051127 |
| Gene Symbol and Synonyms | 1110063P18Rik,2510006J17Rik,ADRM1,ARM-1,ARM1,GP110,OSBPL2,PSMD16,Rpn13 |
| Uniprot Accession | Q16186,Q9JMB5,A1L5A6 |
| Uniprot Entry Name | ADRM1_HUMAN,ADRM1_RAT,ADRM1_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000130706 |
| Target Classification | N/A |
The target: ADRM1, gene name: ADRM1, also named as ARM-1, ARM1, GP110. This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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