Anti-ANS1B/ ANKS1B/ AIDA monoclonal antibody

Anti-ANS1B/ ANKS1B/ AIDA antibody for FACS & in-vivo assay

Target products collectionGo to ANKS1B/ANKS1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1991-Ab-1/ GM-Tg-hg-MP1991-Ab-2Anti-Human ANKS1B monoclonal antibodyHuman
GM-Tg-rg-MP1991-Ab-1/ GM-Tg-rg-MP1991-Ab-2Anti-Rat ANKS1B monoclonal antibodyRat
GM-Tg-mg-MP1991-Ab-1/ GM-Tg-mg-MP1991-Ab-2Anti-Mouse ANKS1B monoclonal antibodyMouse
GM-Tg-cynog-MP1991-Ab-1/ GM-Tg-cynog-MP1991-Ab-2Anti-Cynomolgus/ Rhesus macaque ANKS1B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1991-Ab-1/ GM-Tg-felg-MP1991-Ab-2Anti-Feline ANKS1B monoclonal antibodyFeline
GM-Tg-cang-MP1991-Ab-1/ GM-Tg-cang-MP1991-Ab-2Anti-Canine ANKS1B monoclonal antibodyCanine
GM-Tg-bovg-MP1991-Ab-1/ GM-Tg-bovg-MP1991-Ab-2Anti-Bovine ANKS1B monoclonal antibodyBovine
GM-Tg-equg-MP1991-Ab-1/ GM-Tg-equg-MP1991-Ab-2Anti-Equine ANKS1B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1991-Ab-1/ GM-Tg-hg-MP1991-Ab-2; GM-Tg-rg-MP1991-Ab-1/ GM-Tg-rg-MP1991-Ab-2;
GM-Tg-mg-MP1991-Ab-1/ GM-Tg-mg-MP1991-Ab-2; GM-Tg-cynog-MP1991-Ab-1/ GM-Tg-cynog-MP1991-Ab-2;
GM-Tg-felg-MP1991-Ab-1/ GM-Tg-felg-MP1991-Ab-2; GM-Tg-cang-MP1991-Ab-1/ GM-Tg-cang-MP1991-Ab-2;
GM-Tg-bovg-MP1991-Ab-1/ GM-Tg-bovg-MP1991-Ab-2; GM-Tg-equg-MP1991-Ab-1/ GM-Tg-equg-MP1991-Ab-2
Products NameAnti-ANKS1B monoclonal antibody
Formatmab
Target NameANKS1B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ANKS1B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ANS1B/ ANKS1B/ AIDA VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1991
    Target NameANKS1B
    Gene ID56899,77531,314721,694033,482621,101086662,615777,100052606
    Gene Symbol and SynonymsAIDA,AIDA-1,AIDA-1b,ANKS1B,ANKS2,C030032C09Rik,cajalin-2,E530015N03Rik,EB-1,EB1,Gm10937,Gm1555,RGD1565556
    Uniprot AccessionQ7Z6G8,P0C6S7
    Uniprot Entry NameANS1B_HUMAN,ANS1B_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000185046
    Target ClassificationN/A

    The target: ANKS1B, gene name: ANKS1B, also named as AIDA, AIDA-1, ANKS2, EB-1, EB1, cajalin-2. This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.