Anti-ANX13/ ANXA13/ ISA monoclonal antibody

Anti-ANX13/ ANXA13/ ISA antibody for FACS & in-vivo assay

Target products collectionGo to ANXA13/ANXA13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1992-Ab-1/ GM-Tg-hg-MP1992-Ab-2Anti-Human ANXA13 monoclonal antibodyHuman
GM-Tg-rg-MP1992-Ab-1/ GM-Tg-rg-MP1992-Ab-2Anti-Rat ANXA13 monoclonal antibodyRat
GM-Tg-mg-MP1992-Ab-1/ GM-Tg-mg-MP1992-Ab-2Anti-Mouse ANXA13 monoclonal antibodyMouse
GM-Tg-cynog-MP1992-Ab-1/ GM-Tg-cynog-MP1992-Ab-2Anti-Cynomolgus/ Rhesus macaque ANXA13 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1992-Ab-1/ GM-Tg-felg-MP1992-Ab-2Anti-Feline ANXA13 monoclonal antibodyFeline
GM-Tg-cang-MP1992-Ab-1/ GM-Tg-cang-MP1992-Ab-2Anti-Canine ANXA13 monoclonal antibodyCanine
GM-Tg-bovg-MP1992-Ab-1/ GM-Tg-bovg-MP1992-Ab-2Anti-Bovine ANXA13 monoclonal antibodyBovine
GM-Tg-equg-MP1992-Ab-1/ GM-Tg-equg-MP1992-Ab-2Anti-Equine ANXA13 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1992-Ab-1/ GM-Tg-hg-MP1992-Ab-2; GM-Tg-rg-MP1992-Ab-1/ GM-Tg-rg-MP1992-Ab-2;
GM-Tg-mg-MP1992-Ab-1/ GM-Tg-mg-MP1992-Ab-2; GM-Tg-cynog-MP1992-Ab-1/ GM-Tg-cynog-MP1992-Ab-2;
GM-Tg-felg-MP1992-Ab-1/ GM-Tg-felg-MP1992-Ab-2; GM-Tg-cang-MP1992-Ab-1/ GM-Tg-cang-MP1992-Ab-2;
GM-Tg-bovg-MP1992-Ab-1/ GM-Tg-bovg-MP1992-Ab-2; GM-Tg-equg-MP1992-Ab-1/ GM-Tg-equg-MP1992-Ab-2
Products NameAnti-ANXA13 monoclonal antibody
Formatmab
Target NameANXA13
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ANXA13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ANX13/ ANXA13/ ISA VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm002284mouse Anxa13 Lentivirus plasmid
    ORF Viral VectorvGMLPm002284mouse Anxa13 Lentivirus particle


    Target information

    Target IDGM-MP1992
    Target NameANXA13
    Gene ID312,69787,362915,705013,403935,101080943,614415,100067174
    Gene Symbol and Synonyms1810034H17Rik,ANX13,ANXA13,ISA
    Uniprot AccessionP27216,Q29471
    Uniprot Entry NameANX13_HUMAN,ANX13_CANLF
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000104537
    Target ClassificationN/A

    The target: ANXA13, gene name: ANXA13, also named as ANX13, ISA. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.