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Anti-ARAP1/ CENTD2 monoclonal antibody
Anti-ARAP1/ CENTD2 antibody for FACS & in-vivo assay
Go to ARAP1/ARAP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1995-Ab-1/ GM-Tg-hg-MP1995-Ab-2 | Anti-Human ARAP1 monoclonal antibody | Human |
| GM-Tg-rg-MP1995-Ab-1/ GM-Tg-rg-MP1995-Ab-2 | Anti-Rat ARAP1 monoclonal antibody | Rat |
| GM-Tg-mg-MP1995-Ab-1/ GM-Tg-mg-MP1995-Ab-2 | Anti-Mouse ARAP1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1995-Ab-1/ GM-Tg-cynog-MP1995-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ARAP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1995-Ab-1/ GM-Tg-felg-MP1995-Ab-2 | Anti-Feline ARAP1 monoclonal antibody | Feline |
| GM-Tg-cang-MP1995-Ab-1/ GM-Tg-cang-MP1995-Ab-2 | Anti-Canine ARAP1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1995-Ab-1/ GM-Tg-bovg-MP1995-Ab-2 | Anti-Bovine ARAP1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1995-Ab-1/ GM-Tg-equg-MP1995-Ab-2 | Anti-Equine ARAP1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1995-Ab-1/ GM-Tg-hg-MP1995-Ab-2; GM-Tg-rg-MP1995-Ab-1/ GM-Tg-rg-MP1995-Ab-2; GM-Tg-mg-MP1995-Ab-1/ GM-Tg-mg-MP1995-Ab-2; GM-Tg-cynog-MP1995-Ab-1/ GM-Tg-cynog-MP1995-Ab-2; GM-Tg-felg-MP1995-Ab-1/ GM-Tg-felg-MP1995-Ab-2; GM-Tg-cang-MP1995-Ab-1/ GM-Tg-cang-MP1995-Ab-2; GM-Tg-bovg-MP1995-Ab-1/ GM-Tg-bovg-MP1995-Ab-2; GM-Tg-equg-MP1995-Ab-1/ GM-Tg-equg-MP1995-Ab-2 |
| Products Name | Anti-ARAP1 monoclonal antibody |
| Format | mab |
| Target Name | ARAP1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ARAP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ARAP1/ CENTD2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1995 |
| Target Name | ARAP1 |
| Gene ID | 116985,69710,361617,718488,485207,101095128,511889,100052506 |
| Gene Symbol and Synonyms | 2410002L19Rik,ARAP1,CENTD2,cnt-d2,mKIAA0782 |
| Uniprot Accession | Q96P48 |
| Uniprot Entry Name | ARAP1_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000186635 |
| Target Classification | N/A |
The target: ARAP1, gene name: ARAP1, also named as CENTD2. The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
