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Anti-ASPC1/ ASPSCR1/ ASPCR1 monoclonal antibody
Anti-ASPC1/ ASPSCR1/ ASPCR1 antibody for FACS & in-vivo assay
Go to ASPSCR1/ASPSCR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2010-Ab-1/ GM-Tg-hg-MP2010-Ab-2 | Anti-Human ASPSCR1 monoclonal antibody | Human |
| GM-Tg-rg-MP2010-Ab-1/ GM-Tg-rg-MP2010-Ab-2 | Anti-Rat ASPSCR1 monoclonal antibody | Rat |
| GM-Tg-mg-MP2010-Ab-1/ GM-Tg-mg-MP2010-Ab-2 | Anti-Mouse ASPSCR1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2010-Ab-1/ GM-Tg-cynog-MP2010-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ASPSCR1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2010-Ab-1/ GM-Tg-felg-MP2010-Ab-2 | Anti-Feline ASPSCR1 monoclonal antibody | Feline |
| GM-Tg-cang-MP2010-Ab-1/ GM-Tg-cang-MP2010-Ab-2 | Anti-Canine ASPSCR1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2010-Ab-1/ GM-Tg-bovg-MP2010-Ab-2 | Anti-Bovine ASPSCR1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2010-Ab-1/ GM-Tg-equg-MP2010-Ab-2 | Anti-Equine ASPSCR1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2010-Ab-1/ GM-Tg-hg-MP2010-Ab-2; GM-Tg-rg-MP2010-Ab-1/ GM-Tg-rg-MP2010-Ab-2; GM-Tg-mg-MP2010-Ab-1/ GM-Tg-mg-MP2010-Ab-2; GM-Tg-cynog-MP2010-Ab-1/ GM-Tg-cynog-MP2010-Ab-2; GM-Tg-felg-MP2010-Ab-1/ GM-Tg-felg-MP2010-Ab-2; GM-Tg-cang-MP2010-Ab-1/ GM-Tg-cang-MP2010-Ab-2; GM-Tg-bovg-MP2010-Ab-1/ GM-Tg-bovg-MP2010-Ab-2; GM-Tg-equg-MP2010-Ab-1/ GM-Tg-equg-MP2010-Ab-2 |
| Products Name | Anti-ASPSCR1 monoclonal antibody |
| Format | mab |
| Target Name | ASPSCR1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ASPSCR1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ASPC1/ ASPSCR1/ ASPCR1 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2010 |
| Target Name | ASPSCR1 |
| Gene ID | 79058,68938,691026,715326,475925,101101178,515670,100054827 |
| Gene Symbol and Synonyms | 1190006K01Rik,ASPC,ASPCR1,ASPL,ASPS,ASPSCR1,RCC17,TUG,UBXD9,UBXN9 |
| Uniprot Accession | Q9BZE9 |
| Uniprot Entry Name | ASPC1_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000169696 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: ASPSCR1, gene name: ASPSCR1, also named as ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9. The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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