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Anti-BAIP2/ BAIAP2/ BAP2 monoclonal antibody
Anti-BAIP2/ BAIAP2/ BAP2 antibody for FACS & in-vivo assay
Go to BAIAP2/BAIAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2015-Ab-1/ GM-Tg-hg-MP2015-Ab-2 | Anti-Human BAIAP2 monoclonal antibody | Human |
| GM-Tg-rg-MP2015-Ab-1/ GM-Tg-rg-MP2015-Ab-2 | Anti-Rat BAIAP2 monoclonal antibody | Rat |
| GM-Tg-mg-MP2015-Ab-1/ GM-Tg-mg-MP2015-Ab-2 | Anti-Mouse BAIAP2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2015-Ab-1/ GM-Tg-cynog-MP2015-Ab-2 | Anti-Cynomolgus/ Rhesus macaque BAIAP2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2015-Ab-1/ GM-Tg-felg-MP2015-Ab-2 | Anti-Feline BAIAP2 monoclonal antibody | Feline |
| GM-Tg-cang-MP2015-Ab-1/ GM-Tg-cang-MP2015-Ab-2 | Anti-Canine BAIAP2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2015-Ab-1/ GM-Tg-bovg-MP2015-Ab-2 | Anti-Bovine BAIAP2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2015-Ab-1/ GM-Tg-equg-MP2015-Ab-2 | Anti-Equine BAIAP2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2015-Ab-1/ GM-Tg-hg-MP2015-Ab-2; GM-Tg-rg-MP2015-Ab-1/ GM-Tg-rg-MP2015-Ab-2; GM-Tg-mg-MP2015-Ab-1/ GM-Tg-mg-MP2015-Ab-2; GM-Tg-cynog-MP2015-Ab-1/ GM-Tg-cynog-MP2015-Ab-2; GM-Tg-felg-MP2015-Ab-1/ GM-Tg-felg-MP2015-Ab-2; GM-Tg-cang-MP2015-Ab-1/ GM-Tg-cang-MP2015-Ab-2; GM-Tg-bovg-MP2015-Ab-1/ GM-Tg-bovg-MP2015-Ab-2; GM-Tg-equg-MP2015-Ab-1/ GM-Tg-equg-MP2015-Ab-2 |
| Products Name | Anti-BAIAP2 monoclonal antibody |
| Format | mab |
| Target Name | BAIAP2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-BAIAP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species BAIP2/ BAIAP2/ BAP2 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm003485 | mouse Baiap2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003485 | mouse Baiap2 Lentivirus particle |
Target information
| Target ID | GM-MP2015 |
| Target Name | BAIAP2 |
| Gene ID | 10458,108100,117542,100428388,403473,101087366,507837,100050207 |
| Gene Symbol and Synonyms | BAIAP2,BAP2,FLAF3,IRSP53,IRSP53S,WAML |
| Uniprot Accession | Q9UQB8,Q6GMN2,Q5EAD0 |
| Uniprot Entry Name | BAIP2_HUMAN,BAIP2_RAT,BAIP2_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000175866 |
| Target Classification | N/A |
The target: BAIAP2, gene name: BAIAP2, also named as BAP2, FLAF3, IRSP53. The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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